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PLA2G4A encodes a member of the cytosolic phospholipase A2 group IV family. Additionally we are shipping phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) Kits (35) and phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) Proteins (9) and many more products for this protein.
Showing 10 out of 116 products:
Human Monoclonal PLA2G4A Primary Antibody for ELISA, WB - ABIN393430
Fehér, Juhász, Rimanóczy, Kálmán, Janka: Association study of interferon-γ, cytosolic phospholipase A2, and cyclooxygenase-2 gene polymorphisms in Alzheimer disease. in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2010
Show all 5 references for ABIN393430
Human Polyclonal PLA2G4A Primary Antibody for FACS, IF - ABIN652449
Sharp, White, Chiou, Goodson, Gamboa, McClure, Burgett, Hoskins, Skatrud, Sportsman: Molecular cloning and expression of human Ca(2+)-sensitive cytosolic phospholipase A2. in The Journal of biological chemistry 1991
Show all 2 references for ABIN652449
Human Polyclonal PLA2G4A Primary Antibody for EIA, WB - ABIN453281
Clark, Lin, Kriz, Ramesha, Sultzman, Lin, Milona, Knopf: A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP. in Cell 1991
Show all 2 references for ABIN453281
Human Polyclonal PLA2G4A Primary Antibody for ELISA, WB - ABIN4345947
Gubern, Barceló-Torns, Barneda, López, Masgrau, Picatoste, Chalfant, Balsinde, Balboa, Claro: JNK and ceramide kinase govern the biogenesis of lipid droplets through activation of group IVA phospholipase A2. in The Journal of biological chemistry 2009
Data show that glycation end products (AGE) increase PIP2 production, arachidonic acid release and reactive oxygen species via cytosolic phospholipase A2 activation, and inhibit Na+ K+ ATPase (show ATP1A1 Antibodies) surface expression via PIP5Kgamma (show PIP5K1C Antibodies).
The data emphasize the importance of the PLCeta2 EF-hand domain and articulation of PLCeta2 with LIMK-1 (show LIMK1 Antibodies) in regulating neuritogenesis.
show that accumulation of Abeta (show APP Antibodies) induced elevation of APP (show APP Antibodies) protein expression mediated by cPLA2 alpha, PGE2 release, and CREB (show CREB1 Antibodies) activation via protein kinase A pathway
Prostaglandins from cPLA2-alpha/COX1 (show COX1 Antibodies) pathway and mitogen-activated protein kinases regulate gene expression in Candida albicans-infected macrophages.
Thymocyte maturation can occur independently of cPLA2-alpha.
The study reports the formation of a multiprotein complex at the G2-to-M transition in vitro and in vivo. Group IVA cytosolic phospholipase A2 (cPLA2-alpha) acts as a bridge in this complex to promote binding of SIRT2 (show SIRT2 Antibodies) to cyclin A (show CCNA2 Antibodies)-Cdk2 (show CDK2 Antibodies).
osteoblastic cytosolic phospholipase A2 is crucially involved in ET-1 (show EDN1 Antibodies)-induced prostaglandin formation.
Data indicate that cytosolic phospholipase A2alpha (cPLA2alpha) mediates interleukin 6 (IL6 (show IL6 Antibodies)) induction by Pseudomonas aeruginosa pulmonary infection.
our data indicate that SR-A (show MSR1 Antibodies) localizes in LRs (show LARS Antibodies) and that LRs (show LARS Antibodies) are required to couple SR-A (show MSR1 Antibodies) to PLA2 (show PLA2G2A Antibodies) activation during SRA (show MSR1 Antibodies)-mediated macrophage attachment.
cPLA2 participates in CRHR1 (show CRHR1 Antibodies)-induced apoptosis and CRHR2 (show CRHR2 Antibodies)-inhibited apoptosis.
cPLA2 deletion ameliorates motor deficits and reduces cell loss and tissue damage after spinal cord injury.
genetic association study in Quebec City population: Data suggest total plasma n-6 fatty acid phospholipid levels and C-reactive protein (show CRP Antibodies) are modulated by SNPs in PLA2G4A and PLA2G6 (show PLA2G6 Antibodies) alone or in combination with fish oil dietary supplementation.
cPLA2alpha plays an important role in cell cycle re-entry by quiescent prostate cancer cells
These studies constitute a definitive account, demonstrating the fundamental role of cPLA2alpha to eicosanoid formation and cellular responses within the human circulation.
EGF (show EGF Antibodies) stimulates platelet-activating factor production in ovarian cancer cells in a manner that requires cPLA2.
We conclude that cPLA2alpha is required for sustaining AKT (show AKT1 Antibodies) phosphorylation at Ser473 and cell proliferation in colorectal cancer cells with PI3K (show PIK3CA Antibodies) mutation
alphaSN triggered synapse damage via hyperactivation of cPLA2
Suggest retinal pigment epithelium metabolism of 7-ketocholesterol occurs by esterification to fatty acids via cPLA2alpha and SOAT1 (show SOAT1 Antibodies) followed by selective efflux to HDL (show HSD11B1 Antibodies).
Data indicate 3-(1-Aryl-1H-indol-5-yl)propanoic acids a potent inhibitor of cytosolic phospholipase A2alpha (cPLA2alpha).
result suggests that cPLAPgamma may act as a G protein, activating cPLA(2)alpha prior to reaching full intracellular Ca(2 (show CA2 Antibodies) ) concentrations
Ovulation is associated with an LH/hCG (show CGA Antibodies)-dependent induction of PLA2G4A in GC via the adenylyl cyclase/cAMP pathway.
Activation of cytosolic phospholipase A2 and fatty acid transacylase is essential but not sufficient for thrombin (show F2 Antibodies)-induced smooth muscle cell proliferation.
The results indicate that PLA2 (show YWHAZ Antibodies) activity in equine endometrium changes with the stage of the oestrous cycle and thus may be influenced by systemic hormone concentrations.
During pregnancy, PLA2 (show YWHAZ Antibodies) expression may be sufficient to initiate the cascade for prostaglandin f2alpha secretion and does not play a direct role in maternal recognition of pregnancy.
This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.
cytosolic phospholipase A2
, phospholipase A2 group IVA
, Phospholipase A2 group IVA
, Cytosolic phospholipase A2 (CPLA2)
, Type IV PLA2
, cytosolic PLA2
, phospholipase A2, group 4
, calcium-dependent phospholipid-binding protein
, phosphatidylcholine 2-acylhydrolase
, phospholipase A2 cytosolic
, phospholipase A2, group IB (pancreas)