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may act as a downstream mediator of immune response in IgE receptor signaling; may transport phospholipids in the plasma membrane. Additionally we are shipping phospholipid Scramblase 1 Antibodies (40) and phospholipid Scramblase 1 Proteins (8) and many more products for this protein.
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directed mutagenesis revealed the importance of c-Myc (show MYC ELISA Kits) binding sites from -751 to -756 and -548 to -553 on the promoter of hPLSCR1in transcriptionally regulating the expression of hPLSCR1.
PLSCR1 positively regulates hepatic carcinoma cell proliferation and migration through interacting with midkine (show MDK ELISA Kits)
Suggest role for PLSCR1 in negatively regulating trophoblast fusion rather than directly promoting fusion.
PLSCR1 mediates the antiviral activity and anticarcinogenesis against hepatitis B virus by regulating HBx stability.
affinity of SCR for cholesterol-rich domains in membranes
The C-terminal transmembrane domain of human phospholipid scramblase 1 is essential for the protein flip-flop activity and Ca(2 (show CA2 ELISA Kits))-binding.
This is the first report showing the transcriptional regulation of hPLSCR1 expression by Snail (show SNAI1 ELISA Kits) TF and its possible implications in cancer progression.
PLSCR1 interacted with ANG (show ANG ELISA Kits) in the cell nucleus and regulated rRNA transcription.
hPLSCR1 and PRD-hPLSCR2 showed Ca(2 (show CA2 ELISA Kits)+)-dependent aggregation and scrambling activity
The data are in agreement with the possibility that PLSCR1 is an integral membrane protein.
Phospholipid scramblase 1 regulates phosphatidylserine exposure in response to oxygen stress, leading to beta2-glycoprotein I and IgM binding and lipid-mediated, inflammatory responses.
Lipopolysaccharide treatment resulted in increased expression of phospholipid scramblase 1(PLSCR-1) and decrease in phospholipid scramblase 4(Plscr4 )messenger RNA demonstrating modulation of PLSCR-1 and PLSCR-4 in lipopolysaccharide-induced preterm birth
Study demonstrates that PLSCR1 is a TLR9 (show TLR9 ELISA Kits)-interacting protein that plays an important role in pDC's type 1 IFN responses by regulating TLR9 (show TLR9 ELISA Kits) trafficking to the endosomal compartment.
the capacity of PLSCR1 to augment G-CSF (show CSF3 ELISA Kits)-dependent production of mature neutrophils from myeloid progenitors is unrelated to its reported activities at the endofacial surface of the plasma membrane but does require entry of the protein into the nucleus
PLSCR1 appears to influence progression of UV-induced apoptosis and could be a point of regulation or intervention during programmed cell death
PLSCR1, which is itself an IFN-stimulated gene-encoded protein, provides a mechanism for amplifying and enhancing the IFN response through increased expression of a select subset of potent antiviral genes
PLSCR1 binds to the promoter region of the IP3R1 (show ITPR1 ELISA Kits) gene to enhance its expression
These findings demonstrate a functional interdependence between onzin and PLSCR1.
These data provide evidence that PLSCR1 is a positive intracellular acute phase protein (show ORM1 ELISA Kits) with a tissue-specific mechanism for up-regulation.
may act as a downstream mediator of immune response in IgE receptor signaling\; may transport phospholipids in the plasma membrane
phospholipid scramblase 1
, PL scramblase 1
, ca(2+)-dependent phospholipid scramblase 1
, phospholipid scramblase 2
, erythrocyte phospholipid scramblase
, transplantability-associated protein 1
, PL scramblase 2
, ca(2+)-dependent phospholipid scramblase 2