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phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1) ELISA Kits

PRPS1 encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Additionally we are shipping PRPS1 Proteins (18) and PRPS1 Antibodies (13) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human PRPS1 PRPS1 5631 P60891
Anti-Mouse PRPS1 PRPS1 19139 Q9D7G0
PRPS1 29562 P60892
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Top PRPS1 ELISA Kits at antibodies-online.com

Showing 2 out of 3 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Rat 3.9 pg/ml 15.6-1000 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Cow
96 Tests Log in to see 11 to 13 Days
$1,029.60
Details

More ELISA Kits for PRPS1 Interaction Partners

Human phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1) interaction partners

  1. evaluation of current literature on PRPS1-related syndromes and summaries of potential therapies [review]

  2. analysis of intrafamilial phenotypic variation associated with a single PRPS1 mutation in syndromic or nonsyndromic hearing impairment

  3. CRC (show CALR ELISA Kits) cells that overexpressed miR124 or with knockdown of RPIA (show RPIA ELISA Kits) or PRPS1 had reduced DNA synthesis and proliferation, whereas cells incubated with an inhibitor of miR124 had significantly increased DNA synthesis and proliferation and formed more colonies.

  4. Study identified the critical region in the ARTS promoter and demonstrated that the Sp1 transcription factor (show SP1 ELISA Kits) could regulate the activity of the ARTS promoter through multiple Sp1 (show PSG1 ELISA Kits) binding sites.

  5. Females with a missense mutation in PRPS1, exhibit neuropathy, hearing loss and retinopathy.

  6. the de novo purine synthesis inhibitor lometrexol effectively abrogated PRPS1 mutant-driven drug resistance.

  7. The expression of different genes encoding subunits of PRPS (show MSMB ELISA Kits) enzyme is affected by hypoxia in tumor glioma cells, but the effect of hypoxia is modified by suppression of endoplasmic reticulum stress signaling enzyme ERN1 (show ERN1 ELISA Kits).

  8. respective phenotypic presentation seems to be determined by the exact PRPS1 mutation and the residual enzyme activity, the latter being largely influenced by the degree of skewed X-inactivation

  9. The crystal structure of the ADP-binding pocket of the PRPS1 D52H-mutant and evidence of reduced inhibitor sensitivity.

  10. Review: discuss role of PRPS1 mutations in hearing loss.

Mouse (Murine) phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1) interaction partners

  1. Only unedited pri-miR (show MLXIP ELISA Kits)-376 RNAs were detected in the cochlea suggesting that the activity of PRPS1 in the inner ear may not be regulated through the editing of miR (show MLXIP ELISA Kits)-376 cluster.

  2. PRPS1 loss of function mutations cause a type of nonsyndromic X-linked sensorineural deafness, DFN2

PRPS1 Antigen Profile

Antigen Summary

This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PRPS1

  • phosphoribosyl pyrophosphate synthetase 1 (PRPS1) antibody
  • phosphoribosyl pyrophosphate synthetase 1 (Prps1) antibody
  • ribose-phosphate pyrophosphokinase I -like (LOC314140) antibody
  • 2310010D17Rik antibody
  • ARTS antibody
  • C76571 antibody
  • C76678 antibody
  • CMTX5 antibody
  • DFN2 antibody
  • DFNX1 antibody
  • PPRibP antibody
  • Prps-1 antibody
  • PRS-I antibody
  • PRSI antibody

Protein level used designations for PRPS1

dJ1070B1.2 (phosphoribosyl pyrophosphate synthetase 1) , deafness 2, perceptive, congenital , deafness, X-linked 2, perceptive, congenital , phosphoribosyl pyrophosphate synthase I , ribose-phosphate diphosphokinase 1 , ribose-phosphate pyrophosphokinase 1 , phosphoribosyl pyrophosphate synthetase I , PRS-I

GENE ID SPECIES
5631 Homo sapiens
19139 Mus musculus
29562 Rattus norvegicus
781227 Bos taurus
314140 Rattus norvegicus
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