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ARHGAP18 belongs to a family of Rho (see MIM 165390) GTPase-activating proteins that modulate cell signaling (Potkin et al., 2009 [PubMed 19065146]).[supplied by OMIM, Apr 2010].. Additionally we are shipping ARHGAP18 Antibodies (48) and many more products for this protein.
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Our results show that miR (show MLXIP Proteins)-181a is down-regulated in glioblastoma multiforme (GBM) patients. The three target genes, ANGPT2 (show ANGPT2 Proteins), ARHGAP18 and LAMC1 (show LAMC1 Proteins), are negatively correlated with the expression of miR (show MLXIP Proteins)-181a. Moreover, high expression of ANGPT2 (show ANGPT2 Proteins) or LAMC1 (show LAMC1 Proteins) together with large size of GBM is correlated with a shorter median overall survival
Results describe ARHGAP18 as a novel negative regulator of sprouting by acting dualistically to limit tip cell formation and to maintain junctional integrity.
The results define ARHGAP18 as one of the crucial factors for the regulation of RhoA (show RHOA Proteins) for the control of cell shape, spreading, and migration.
identification of a novel gene, SENEX, that regulates stress induced premature senescence pathways in endothelial cells involving p16(INK4a) and retinoblastoma protein activation
This study use Functional MRI (show C7ORF49 Proteins) and Genome Wide Association Analysis indentic novel gene(ARHGAP18) associated with schizophrenia.
ARHGAP18 belongs to a family of Rho (see MIM 165390) GTPase-activating proteins that modulate cell signaling (Potkin et al., 2009
Rho GTPase activating protein 18
, rho GTPase-activating protein 18
, rho GTPase-activating protein 18-like
, rho-type GTPase-activating protein 18