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Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. Additionally we are shipping rho Guanine Nucleotide Exchange Factor (GEF) 5 Antibodies (73) and many more products for this protein.
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Tim protein and DDX11 (show DDX11 Proteins) physically and functionally interact and act in concert to preserve replication fork progression in perturbed conditions.
Data indicate that Rho guanine nucleotide exchange factor 5 (ARHGEF5) is expressed in most human lung adenocarcinoma tissues and cell lines.
Targeting rho guanine nucleotide exchange factor ARHGEF5/TIM with auto-inhibitory peptides in human breast cancer.
The auto-inhibitory state of Rho guanine nucleotide exchange factor ARHGEF5/TIM can be relieved by targeting its SH3 domain with rationally designed peptide aptamers.
In conclusion, ARHGEF5/Src (show SRC Proteins) can be considered as a prognostic biomarker and a therapeutic target for patients with resected NSCLC.
A receiver operating characteristic curve constructed with HSP105 (show HSPH1 Proteins) and TIM gave a sensitivity of 54.3% and 95% (38/40) specificity in discriminating esophageal squamous cell carcinoma from matched controls.
This study performed whole exome sequencing demonistrated that the true de novo variants represent mutations in genes (KCNH5 (show KCNH5 Proteins), CLCN4 (show CLCN4 Proteins), and ARHGEF15 (show ARHGEF15 Proteins)) not previously associated with epilepsies in humans.
Tim-Tipin (show TIPIN Proteins) complex might play a role in coupling DNA unwinding and DNA synthesis by directly affecting the catalytic activities of replication fork proteins.
Overexpression of Arhgef5 promoted actin stress fiber remodeling through activating RhoA (show RHOA Proteins), and the activation of RhoA (show RHOA Proteins) or Cdc42 (show CDC42 Proteins) was required for Src (show SRC Proteins)-induced podosome formation.
association in humans of TIM-1 and hypersensitivity and the relationship between TIM1, hygiene, and the environment.
RhoA (show RHOA Proteins) guanine nucleotide exchange factor (show ARHGEF12 Proteins) Arhgef5 regulates immature dendritic cell migration
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.
Rho guanine nucleotide exchange factor (GEF) 5
, rho guanine nucleotide exchange factor 5
, rho guanine nucleotide exchange factor 5-like
, guanine nucleotide regulatory protein TIM
, oncogene TIM
, p60 TIM
, transforming immortalized mammary oncogene