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anti-rho-Related BTB Domain Containing 2 (RHOBTB2) Antibodies

The protein encoded by RHOBTB2 is a small Rho GTPase and a candidate tumor suppressor. Additionally we are shipping rho-Related BTB Domain Containing 2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RHOBTB2 23221 Q9BYZ6
RHOBTB2 246710 Q91V93
RHOBTB2 306004  
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Top anti-rho-Related BTB Domain Containing 2 Antibodies at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human breast carcinoma labeled with Anti DBC2 Polyclonal Antibody, Unconjugated (ABIN706241) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded ovarian cancer xenograft labeled with Anti-DBC2 receptor Polyclonal Antibody, Unconjugated (ABIN706241) followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged RHOBTB2 is 0.1 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$449.17
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$449.17
Details
Human Rabbit Un-conjugated WB   0.2 mg Log in to see 9 to 11 Days
$346.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of RHOBTB2 expression in transfected 293T cell line by RHOBTB2 MaxPab polyclonal antibody.Lane 1: RHOBTB2 transfected lysate(79.97 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB   50 μg Log in to see 11 to 13 Days
$478.80
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry of Human thyroid cancer using RHOBTB2 Polyclonal Antibody at dilution of 1:30 200 μL Log in to see 8 to 9 Days
$588.50
Details

RHOBTB2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
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Mouse (Murine) ,


Rat (Rattus) ,


More Antibodies against rho-Related BTB Domain Containing 2 Interaction Partners

Human rho-Related BTB Domain Containing 2 (RHOBTB2) interaction partners

  1. Mutation in the promoter and exon 7 of DBC2 gene is not common in the Chinese population and may not contribute to the susceptibility for breast cancer in China

  2. data suggest a new paradigm for Hsp90 (show HSP90 Antibodies)-modulated assembly of a Cul3 (show CUL3 Antibodies)/DBC2 E3 ubiquitin ligase (show MUL1 Antibodies) complex that may extend to other E3 ligase complexes.

  3. ). The results demonstrated that aberrant methylation of RhoBTB2 may be responsible for the suppression of RhoBTB2 mRNA expression in breast cancer, a significant event during the genesis of breast cancer that correlated with progesterone receptor (show PGR Antibodies) status

  4. Thus loss of DBC2 expression is caused by abnormal methylation of DBC2 and might have a role in breast cancer development.

  5. Loss of DBC2 expression is an early and progressive event in the development of lung adenocarcinoma.

  6. Overexpression of RhoBTB2 in breast tumor cells significantly inhibited the proliferation and colony formation of tumor cells. In addition, RhoBTB2 also elevated the apoptotic ratio and caused typical changes of apoptotic morphology.

  7. RhoBTB2 is establishing itself as a tumor suppressor with increasing relevance towards malignancies.

  8. Ectopic expression of RhoBTB2 results in decreased phosphorylation of ezrin (show EZR Antibodies) and Akt2 (show AKT2 Antibodies) in both MDA-MB-231 and MDA-MB-435 cells.

  9. The expression of Fas (show FAS Antibodies), CTLA-4 (show CTLA4 Antibodies) and RhoBTB2 at the mRNA level is involved in genesis and progression of breast cancer.

  10. Frequent loss of RhoBTB2 expression is associated with sporadic breast cancer.

Mouse (Murine) rho-Related BTB Domain Containing 2 (RHOBTB2) interaction partners

  1. There is no connection between elevated expression of mDbc2/Rhobtb2 and a specific stage of mammary gland development, but this gene plays a critical role in the development of the nervous system.

rho-Related BTB Domain Containing 2 (RHOBTB2) Antigen Profile

Protein Summary

The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RHOBTB2

  • tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B) antibody
  • Rho-related BTB domain containing 2 (RHOBTB2) antibody
  • Rho-related BTB domain containing 2 (LOC100352605) antibody
  • Rho-related BTB domain containing 2 (Rhobtb2) antibody
  • Dbc2 antibody
  • E130206H14Rik antibody
  • mKIAA0717 antibody
  • TVB antibody

Protein level used designations for RHOBTB2

tumor necrosis factor receptor superfamily member 10B , rho-related BTB domain-containing protein 2 , Rho-related BTB domain containing 2 , subgroup E ALV receptor , rho-related BTB domain-containing protein 2-like , deleted in breast cancer 2 gene protein , p83 , deleted in breast cancer 2 gene protein homolog

GENE ID SPECIES
373904 Gallus gallus
419536 Gallus gallus
464050 Pan troglodytes
486120 Canis lupus familiaris
664712 Meleagris gallopavo
716607 Macaca mulatta
784567 Bos taurus
100030651 Monodelphis domestica
100057764 Equus caballus
100174455 Pongo abelii
100352605 Oryctolagus cuniculus
100414447 Callithrix jacchus
100602112 Nomascus leucogenys
23221 Homo sapiens
246710 Mus musculus
306004 Rattus norvegicus
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