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RHOBTB3 is a member of the evolutionarily conserved RHOBTB subfamily of Rho GTPases. Additionally we are shipping RHOBTB3 Proteins (4) and many more products for this protein.
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Human Polyclonal RHOBTB3 Primary Antibody for IHC, ELISA - ABIN1535304
Ramos, Khademi, Somesh, Rivero: Genomic organization and expression profile of the small GTPases of the RhoBTB family in human and mouse. in Gene 2002
RHOBTB3 serves as a scaffold to organize a multi-subunit complex that promotes the hydroxylation, ubiquitination and degradation of HIFalpha.
Reveal a novel role for a RhoBTB3 in catalyzing cyclin E (show CCNE1 Antibodies) turnover during S phase, as well as an unexpected, essential role for the Golgi as a ubiquitylation platform for cell cycle control.
The interaction between RhoBTB3 and the 5-HT7a receptor strongly inhibits proteasomal degradation of the 5-HT7a receptor.
Study reports that the atypical Rho GTPase (show RACGAP1 Antibodies) family member, RhoBTB3, binds directly to Rab9 (show RAB9A Antibodies) GTPase (show RACGAP1 Antibodies) and functions with Rab9 (show RAB9A Antibodies) in protein transport from endosomes to the trans Golgi network.
The authors identified MUF1 as the first substrate for RhoBTB-Cul3 ubiquitin ligase complexes.
RHOBTB3 is a member of the evolutionarily conserved RHOBTB subfamily of Rho GTPases. For background information on RHOBTBs, see RHOBTB1 (MIM 607351).
Rho-related BTB domain containing 3
, KIAA0878 protein-like
, rho-related BTB domain-containing protein 3
, rho-related BTB domain-containing protein 3-like