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anti-serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) Antibodies

The protein encoded by SPINK1 is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. Additionally we are shipping serine Peptidase Inhibitor, Kazal Type 1 Kits (18) and serine Peptidase Inhibitor, Kazal Type 1 Proteins (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SPINK1 266602 P09656
SPINK1 6690 P00995
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Top anti-serine Peptidase Inhibitor, Kazal Type 1 Antibodies at antibodies-online.com

Showing 10 out of 66 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SPINK1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p) 7 mL Log in to see 21 to 31 Days
$377.00
Details
Human Mouse Un-conjugated IHC (p), IP, ELISA, WB Immunoperoxidase of monoclonal antibody to SPINK1 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 1 ug/ml] SPINK1 monoclonal antibody (M01), clone 4D4. Western Blot analysis of SPINK1 expression in human pancreas. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IF, IHC (p), IP, WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Rat Rabbit Un-conjugated IF (p), IHC (p) Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded rat pancreas labeled with Anti-SPINK1 Polyclonal Antibody, Unconjugated (ABIN681658) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p), WB 1 mL Log in to see 21 to 31 Days
$659.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using SPINK1 antibody. 100 μL Log in to see 9 Days
$302.50
Details
Rat Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

SPINK1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-serine Peptidase Inhibitor, Kazal Type 1 Antibodies

  1. Human Monoclonal SPINK1 Primary Antibody for IHC (p), IP - ABIN562978 : Tomlins, Rhodes, Yu, Varambally, Mehra, Perner, Demichelis, Helgeson, Laxman, Morris, Cao, Cao, Andrén, Fall, Johnson, Wei, Shah, Al-Ahmadie, Eastham, Eggener, Fine, Hotakainen, Stenman, Tsodikov et al.: The role of SPINK1 in ETS rearrangement-negative prostate cancers. ... in Cancer cell 2008 (PubMed)
    Show all 8 references for ABIN562978

More Antibodies against serine Peptidase Inhibitor, Kazal Type 1 Interaction Partners

Human serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) interaction partners

  1. Approx 25% of discontinuously involved prostate biopsy cores showed tumor foci with discordant ERG (show ERG Antibodies)/SPINK1 status, consistent with multiclonal disease.

  2. Letter/Case Report: high penetrance of the PRSS1 (show PRSS1 Antibodies) A16V mutation caused by SPINK1 N34S and CFTR (show CFTR Antibodies) TG11-5T co-mutations associated with pancreatitis.

  3. Identify SPINK1 promoter variants exhibiting significant functional defects that should be considered potential risk factors for chronic pancreatitis.

  4. The SPINK1 protein seems to play a role in tumor proliferation.

  5. neither ERG (show ERG Antibodies) nor SPINK1 appear to be useful biomarkers for prognostication of early stage prostate cancer

  6. The majority of children with genetic predisposition to idiopathic acute and acute recurrent pancreatitis have the SPINK1 mutation.

  7. Patients with SPINK1 N34S mutations were more likely to develop a Dilated duct, Calcifications, and Diabetes as Long-term Outcome of Endoscopic Treatments in Idiopathic Chronic Pancreatitis.

  8. Evidence suggests that SPINK1 is an important growth factor that connects chronic inflammation and cancer.

  9. Over-expression of FOXP1 (show FOXP1 Antibodies) and SPINK1 may participate in the carcinogenesis of hepatitis B virus related cirrhosis.

  10. SPINK1 plays a role as a growth factor, signaling through the EGFR (show EGFR Antibodies) pathway in pancreatic ductal adenocarcinoma and neoplasms, and that the EGFR (show EGFR Antibodies) is involved in the malignant transformation of IPMN.

Cow (Bovine) serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) interaction partners

  1. Partially folded bovine pancreatic trypsin inhibitor analogues attain fully native structures when co-crystallized with S195A rat trypsin.

serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) Antigen Profile

Protein Summary

The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis.

Gene names and symbols associated with SPINK1

  • serine peptidase inhibitor, Kazal type 1 (SPINK1) antibody
  • pancreatic secretory trypsin inhibitor-like (LOC100622575) antibody
  • serine peptidase inhibitor, Kazal type 1 (Spink1) antibody
  • serine peptidase inhibitor, Kazal type 3 (Spink3) antibody
  • PCTT antibody
  • PSTI antibody
  • Psti-1 antibody
  • Spink1 antibody
  • Spink3 antibody
  • TATI antibody
  • TCP antibody
  • Tilp antibody

Protein level used designations for SPINK1

serine peptidase inhibitor, Kazal type 1 , serine protease inhibitor, Kazal type 1 , PSTI-II , calcium transport inhibitor , caltrin , pancreatic secretory trypsin inhibitor II , pancreatic secretory trypsin inhibitor type II (PSTI-II) , serine peptidase inhibitor, Kazal type 3 , serine protease inhibitor Kazal-type 3 , serine protease inhibitor, Kazal type 3 , pancreatic secretory trypsin inhibitor , serine protease inhibitor Kazal-type 1 , tumor-associated trypsin inhibitor , PSTI-I , Serine protease inhibitor kanzal type 1/ Trypsin inhibitor-like protein pancreatic , Serine protease inhibitor, kanzal type 1/ Trypsin inhibitor-like protein, pancreatic , cholecystokinin-releasing peptide , monitor peptide , pancreatic cholecystokinin(CCK) releasing peptide , pancreatic secretory trypsin inhibitor I , trypsin inhibitor-like protein, pancreatic

GENE ID SPECIES
740785 Pan troglodytes
100622575 Sus scrofa
266602 Rattus norvegicus
6690 Homo sapiens
574092 Bos taurus
608433 Canis lupus familiaris
101115618 Ovis aries
24833 Rattus norvegicus
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