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anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6) Antibodies

SERPINA6 encodes an alpha-globulin protein with corticosteroid-binding properties. Additionally we are shipping SERPINA6 Kits (40) and SERPINA6 Proteins (38) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SERPINA6 12401 Q06770
SERPINA6 866 P08185
SERPINA6 299270 P31211
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Top anti-SERPINA6 Antibodies at antibodies-online.com

Showing 10 out of 139 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, WB Confocal immunofluorescent analysis of SERPINA6 Antibody (Center) (ABIN654693) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Rat Goat Un-conjugated EIA, WB AP23762PU-N SERPINA6 antibody staining of Rat Liver lysate at 0.03 µg/ml (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. AP23762PU-N SERPINA6 antibody staining of Rat Liver lysate at 0.03 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Rat Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Confocal immunofluorescent analysis of SERPINA6 Antibody (Center) Cat.-No AP53859PU-N with 293 cell followed by Alexa Fluor 488-conjugated Goat anti-Rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). Western blot analysis of SERPINA6 Antibody (Center) Cat.-No AP53859PU-N in Mouse kidney tissue lysates (35ug/lane). This demonstrates the SERPINA6 antibody detected the SERPINA6 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB Anti-Cortisol Binding Globulin antibody, ICC ICC: HEPG2 Cell Anti-Cortisol Binding Globulin antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: A431 Cell Lysate Lane 3: U87 Cell Lysate Lane 4: 22RV1 Cell Lysate Lane 5: PANC Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Rat Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated EIA, IHC (p) Human Uterus (formalin-fixed, paraffin-embedded) stained with SERPINA6followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Goat Un-conjugated IHC (p), ELISA Human Uterus (formalin-fixed, paraffin-embedded) stained with SERPINA6 antibody ABIN462399 followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Mouse Goat Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Rat Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details

SERPINA6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SERPINA6 Antibodies

  1. Rat (Rattus) Polyclonal SERPINA6 Primary Antibody for ELISA, WB - ABIN625826 : Romero, Holmgren-Holm, Grasa, Esteve, Remesar, Fernández-López, Alemany: Modulation in Wistar rats of blood corticosterone compartmentation by sex and a cafeteria diet. in PLoS ONE 2013 (PubMed)

More Antibodies against SERPINA6 Interaction Partners

Mouse (Murine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6) interaction partners

  1. CBG is involved in the gender differences observed in corticosteroids circulating levels and plays a role in the local regulation of corticosteroids availability in organs like lung.

  2. the same gene encodes brain and liver corticosteroid-binding globulin

  3. Data suggest fine control interaction between plasma CBG upregulation and stress-induced corticosterone (CORT (show CORT Antibodies)) release in mouse model of psychological stress; CBG appears to function in maintaining dynamic equilibrium between CBG-bound/-unbound CORT (show CORT Antibodies).

  4. Sequencing analysis showed that Cbg cDNA obtained from the mouse hypothalamus was homologous to Cbg cDNA obtained from the liver.

  5. Cbg-/- mice, unlike controls, remain insensitive to stress applied before memory retrieval. Furthermore, under stress conditions, we observed a blunted surge of corticosterone (CORT (show CORT Antibodies)) in plasma and no free CORT (show CORT Antibodies) rise in the hippocampus of Cbg-/-.

  6. study describes functional hyporesponsiveness and aldosterone resistance in distal colon of CBG(-/-) mice; steroid actions require an intrinsic but unknown function of CBG, which allows the sufficient supply of the hormone/s to the target tissue

  7. Critical role of plasma Cbg in providing an adequate endocrine and behavioral response to stress.

  8. These data suggest an active role for CBG in bioavailability, local delivery, and/or cellular signal transduction of glucocorticoids that extends beyond a function as a mere cargo transporter.

Human serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6) interaction partners

  1. Human cardiomyocytes express mineralocorticoid receptors, but are mostly free of nuclear glucocorticoid receptors. CBG is expressed in myocardium and in Purkinje fibers. CBG in heart is colocalized with mineralocorticoid receptor (show NR3C2 Antibodies).

  2. SERPINA6-rs1998056 regulated by FOXA/ERalpha (show ESR1 Antibodies) might be associated with female HCC (show FAM126A Antibodies) risk

  3. genetic variation in the SERPINA6 gene may be associated with altered CBG levels during adolescence.

  4. the results suggest that DEX repression of Corticosteroid-binding globulin involves tethering of the glucocorticoid receptor (show NR3C1 Antibodies) to C/EBPb (show CEBPB Antibodies).

  5. 8 naturally occurring CBG mutants with abnormalities in cortisol-binding affinity, cortisol-binding capacity, production/secretion, sensitivity to proteolytic cleavage of the reactive center loop, or recognition by monoclonal antibodies used for ELISAs were identified

  6. The study investigate the half-life of intact and elastase cleaved CBG in the rabbit. The half-lives of intact and cleaved human CBG are 10 h and identical.

  7. CBG is coexpressed with hypothalamic neuropeptides.CBG may be involved in control of systemic and central stress response.

  8. Exome chip and 1000 Genomes imputation analysis of this locus in the CROATIA-Korcula cohort identified missense mutations in SERPINA6 and SERPINA1 (show SERPINA1 Antibodies) that did not account for the effects of common variants

  9. Atomic interactions observed between progesterone and CBG explain the lower affinity of progesterone in comparison to corticosteroids.

  10. investigation of physicochemical, electronic, and structural requirements for selective and effective binding of steroids (many are endogenous steroid metabolites) to CBG and SHBG (show SHBG Antibodies) active/ligand-binding sites

Pig (Porcine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6) interaction partners

  1. non-synonymous polymorphisms of SERPINA6, particularly SNPs c.919G>A and c.44G>T/c.622C>T, are associated with cortisol level, HPA (show HPSE Antibodies) axis activity, and carcass and meat quality traits

  2. Cbg gene is a key regulator of cortisol levels and obesity susceptibility.

  3. Negative relationship exists between plasma cortisol and CBG under conditions of acute stress.

SERPINA6 Antigen Profile

Protein Summary

This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.

Gene names and symbols associated with SERPINA6

  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 (SERPINA6) antibody
  • serpin (serpina6) antibody
  • Corticosteroid-binding globulin-like (LOC100356417) antibody
  • serine (or cysteine) peptidase inhibitor, clade A, member 6 (Serpina6) antibody
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 (Serpina6) antibody
  • AI265318 antibody
  • AV104445 antibody
  • CBG antibody
  • ep45-A antibody
  • SERPINA6 antibody

Protein level used designations for SERPINA6

CBG , corticosteroid-binding globulin , serpin A6 , transcortin , serine protease inhibitor A6 , estrogen-regulated protein EP45 , serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 , corticosteroid binding globulin , serine (or cysteine) proteinase inhibitor, clade A, member 6 , serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 , serine (or cysteine) peptidase inhibitor, clade A, member 6 , serpin peptidase inhibitor, clade A, member 6

GENE ID SPECIES
100172888 Pongo abelii
373636 Xenopus laevis
453131 Pan troglodytes
490838 Canis lupus familiaris
701121 Macaca mulatta
100356417 Oryctolagus cuniculus
12401 Mus musculus
866 Homo sapiens
299270 Rattus norvegicus
396736 Sus scrofa
101118224 Ovis aries
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