anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) Antibodies

The protein encoded by SERPINA1 is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Additionally we are shipping SERPINA1 Kits (55) and SERPINA1 Proteins (55) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SERPINA1 20701 P22599
SERPINA1 5265 P01009
SERPINA1 24648 P17475
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Top anti-SERPINA1 Antibodies at antibodies-online.com

Showing 10 out of 433 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SERPINA1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate WB Suggested Anti-SERPINA1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-SERPINA1 Antibody Titration: 1.25ug/ml ELISA Titer: 1:12500 Positive Control: HepG2 cell lysate SERPINA1 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells WB Suggested Anti-SERPINA1 Antibody Titration: 4.0-8.0 Positive Control: Human kidney lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of SERPINA1 Antibody (Center) Cat.-No AP53855PU-N in A2058 cell line lysates (35ug/lane). SERPINA1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Rabbit Un-conjugated IHC (p), WB Anti- SERPINA1 Picoband antibody, IHC(P) IHC(P): Mouse Spleen Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated DB, ELISA, IHC (p), WB Immunohistochemistry-Paraffin: Serpin A1/alpha 1-Antitrypsin Antibody (2B12) [NBP1-47444] - Analysis of paraffin-embedded breast cancer tissues (left) and liver cancer tissues (right) using BECN1 mouse mAb with DAB staining. ELISA: Serpin A1/alpha 1-Antitrypsin Antibody (2B12) [NBP1-47444] - Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng) 0.1 mL Log in to see 7 to 9 Days
$447.56
Details
Human Rabbit Un-conjugated WB Western blot analysis of SERPINA1 Antibody (Center) (ABIN653381) in A2058 cell line lysates (35 µg/lane). SERPINA1 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: alpha 1 Antitrypsin Antibody [NBP1-90308] - Staining of human kidney shows moderate extra-cellular positivity in cells in tubules. Western Blot: alpha 1 Antitrypsin Antibody [NBP1-90308] - Lane 1: Marker [kDa] 206, 113, 82, 49, 32, 26, 18.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human cell line A-431.Lane 5: Human liver tissue 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Goat Un-conjugated EIA, IF, IHC (p), IP, WB 50 μL Log in to see 6 to 8 Days
$500.50
Details

SERPINA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SERPINA1 Antibodies

  1. Human Polyclonal SERPINA1 Primary Antibody for WB - ABIN2787988 : Koh, Rhee, Kang, Yang, You, Lee, Min, Kim, Nam, Kim: Differential gene expression profiles of metastases in paired primary and metastatic colorectal carcinomas. in Oncology 2008 (PubMed)
    Show all 2 references for 2787988

  2. Human Monoclonal SERPINA1 Primary Antibody for EIA, WB - ABIN1105313 : Liu, Qian, Gritsenko, Camp, Monroe, Moore, Smith: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. in Journal of proteome research 2005 (PubMed)
    Show all 2 references for 1105313

  3. Human Polyclonal SERPINA1 Primary Antibody for IHC, IHC (p) - ABIN4352832 : Lindén, Segersten, Runeson, Wester, Busch, Pettersson, Lind, Malmström: Tumour expression of bladder cancer-associated urinary proteins. in BJU international 2013 (PubMed)

  4. Human Monoclonal SERPINA1 Primary Antibody for DB, ELISA - ABIN4352827 : Hoopes, Willcockson, Caron: Characteristics of multi-organ lymphangiectasia resulting from temporal deletion of calcitonin receptor-like receptor in adult mice. in PLoS ONE 2012 (PubMed)

  5. Human Polyclonal SERPINA1 Primary Antibody for IHC, WB - ABIN2792095 : Knappstein, Ide, Schmidt, Heusipp: Alpha 1-antitrypsin binds to and interferes with functionality of EspB from atypical and typical enteropathogenic Escherichia coli strains. in Infection and immunity 2004 (PubMed)

  6. Human Polyclonal SERPINA1 Primary Antibody for EIA, WB - ABIN950362 : Zhang, Li, Martin, Aebersold: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. in Nature biotechnology 2003 (PubMed)

More Antibodies against SERPINA1 Interaction Partners

Horse (Equine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) interaction partners

  1. Although circulating nucleosomes and elastase - alpha 1-antitrypsin complexes are at present the best characterized biomarkers for neutrophil extracellular traps formation and neutrophil activation, their lack of association with rs2288904 genotype does not exclude a role for SLC44A2 (show SLC44A2 Antibodies) in neutrophil activation (and possibly NET formation) in Venous Thromboembolism.

Chimpanzee serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) interaction partners

  1. The mechanism underlying the alpha(1)PI deficiency that attends HIV-1 infection, was investigated.

Mouse (Murine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) interaction partners

  1. Loss of alpha 1-Antitrypsin is associated with emphysema.

Human serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) interaction partners

  1. AAT (show SERPINA1A Antibodies) heterozygous status in rheumatoid arthritis is strongly associated with positive anti-citrullinated peptide autoantibodies and may define a distinct subset of patients with increased disease severity.

  2. Report alpha-1 antitrypsin Pi*Z gene frequency and Pi*ZZ genotype numbers worldwide.

  3. SNP rs8004738 of SERPINA1 gene significantly interacted with smoking status and was associated with a higher risk for COPD (show ARCN1 Antibodies) in the Chinese population.

  4. tissue specific expression and regulation of short transcripts of SERPINA1 gene and the presence of C-terminal peptides in supernatants from activated neutrophils

  5. SERPINA1 variants are associated with ANCA-associated vasculitis risk.

  6. Report incorporation of the Mmalton allele-specific genotyping assay in the diagnostic algorithm of alpha-1-antitrypsin deficiency.

  7. The expression and intracellular accumulation of mutated Z-alpha-1 antitrypsin (the most common mutation) compromises macrophage function and contributes to emphysema development. Macrophages from individuals with Z-AAT (show SERPINA1A Antibodies) have more proteolytic activity on ECM (show MMRN1 Antibodies) than normal. This abnormal activity is not abrogated by exogenous AAT (show SERPINA1A Antibodies) and may be the result of cellular dysfunction induced by intracellular accumulation of Z-AAT (show SERPINA1A Antibodies).

  8. hAAT inhibits DC activation and function, and it also attenuates autoimmunity and renal damage in the MRL/lpr (show FAS Antibodies) lupus model

  9. The deficiency PI*Z A1AT allele is considerably more common in patients with chronic respiratory disorders than in the general Polish population.

  10. Norursodeoxycholic acid administration is associated with increased autophagy, reduced A1AT protein accumulation, and reduced liver injury in a model of A1AT deficiency.

Cow (Bovine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) interaction partners

  1. Comparisons of the expression patterns of cattle fetuses and their dams show that the PI gene is biallelically expressed in fetuses and predominantly monoallelically expressed in the dams.

SERPINA1 Antigen Profile

Protein Summary

The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with SERPINA1

  • SH2B adaptor protein 2 (Sh2b2) antibody
  • alpha-1-antitrypsin (SPI2) antibody
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (serpina1) antibody
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1) antibody
  • alpha-1-antitrypsin (LOC100328621) antibody
  • serine (or cysteine) preptidase inhibitor, clade A, member 1B (Serpina1b) antibody
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (Serpina1) antibody
  • A1A antibody
  • A1AT antibody
  • AAT antibody
  • alpha-1-PI antibody
  • alpha1AT antibody
  • Aps antibody
  • D12Ucla2 antibody
  • Dom2 antibody
  • MGC64429 antibody
  • Pi antibody
  • PI1 antibody
  • PI2 antibody
  • PRO2275 antibody
  • SERPINA1 antibody
  • serpina1d antibody
  • Spi1 antibody
  • Spi1-2 antibody

Protein level used designations for SERPINA1

alpha-1-antiproteinase S , alpha-1-antitrypsin , alpha-1-proteinase inhibitor , alpha-1-antiproteinase 2 , alpha-1-antitrypsin 2 , alpha-1-proteinase inhibitor 2 , serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 , serine (or cysteine) proteinase inhibitor, clade A, member 1d , serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 , alpha-1 protease inhibitor , alpha-1-antiproteinase , serpin A1 , AAT , alpha-1 protease inhibitor 2 , alpha-1-antitrypsin 1-2 , serine (or cysteine) proteinase inhibitor, clade A, member 1b , serine protease inhibitor 1-2 , serine protease inhibitor A1b , serpin A1b , alpha-1-antitrypsin null , protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin , serine (or cysteine) proteinase inhibitor, clade A, member 1 , alpha-1-antitrypsin (protease inhibitor) , alpha-1-protease inhibitor , serine protease inhibitor alpha 1 , alpha 1 antitrypsin , protease inhibitor 1 (anti-elastase, antitrypsin, alpha-1) , serine (or cysteine) proteinase inhibitor, clade A (alpha-1antiproteinase, antitrypsin), member 1 , serine proteinase inhibitor, clade A, member 1 , alpha-1 antitrypsin , protease inhibitor 1 , Alpha-1 protease inhibitor

GENE ID SPECIES
100379265 Cavia porcellus
100065158 Equus caballus
379963 Xenopus laevis
423434 Gallus gallus
467541 Pan troglodytes
701361 Macaca mulatta
100145012 Xenopus (Silurana) tropicalis
100171544 Pongo abelii
100328621 Oryctolagus cuniculus
20701 Mus musculus
5265 Homo sapiens
24648 Rattus norvegicus
480422 Canis lupus familiaris
397688 Sus scrofa
280699 Bos taurus
443388 Ovis aries
101841330 Mesocricetus auratus
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