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serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 Proteins (SERPINB1)

The protein encoded by SERPINB1 is a member of the serpin family of proteinase inhibitors. Additionally we are shipping serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 Antibodies (105) and serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse SERPINB1 SERPINB1 66222 Q9D154
SERPINB1 1992 P30740
SERPINB1 282222  
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Top serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,036.00
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,036.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,036.00
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$3,039.67
Details
Yeast Horse His tag   1 mg Log in to see 56 to 66 Days
$3,041.50
Details
HOST_Human Human His tag   10 μg Log in to see 5 Days
$154.00
Details
HOST_Baculovirus infected Insect Cells Human His tag 50 μg Log in to see 16 Days
$382.80
Details

SERPINB1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Cow (Bovine)

More Proteins for serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 (SERPINB1) Interaction Partners

Cow (Bovine) serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 (SERPINB1) interaction partners

  1. the function of LEI during wound healing is related to its activity as a protease inhibitor and/or to its anti-apoptotic activity.

Pig (Porcine) serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 (SERPINB1) interaction partners

  1. the function of LEI during wound healing is related to its activity as a protease inhibitor and/or to its anti-apoptotic activity.

Mouse (Murine) serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 (SERPINB1) interaction partners

  1. SerpinB1 is a conserved endogenous secretory protein that promotes proliferation of beta cells.

  2. our findings reveal a novel function of serpinB1 in limiting untoward expansion of lymphocytes with a Th17 phenotype.

  3. SerpinB1 is critical for maintaining polymorphonuclear neutrophils survival by antagonizing intracellular cathepsin G (show CTSG Proteins) activity.

  4. Expression of Leukocyte elastase inhibitor in the ovary and oviduct of infected VDR (show CYP27B1 Proteins)(+/+) mice was greater than that of infected VDR (show CYP27B1 Proteins)(-/-) mice.

Human serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 (SERPINB1) interaction partners

  1. Data show that oropharyngeal squamous cell carcinomas (OPSCCs) express granzyme inhibitors SERPINB1, SERPINB4 (show SERPINB4 Proteins) and SERPINB9 (show SERPINB9 Proteins) for cytotoxicity and the expression was not different between human papillomavirus (HPV)-positive and HPV-negative tumors.

  2. Pediatric CNS-PNETs evade immune recognition by downregulating cell surface MHC (show HLAE Proteins)-I and CD1d (show CD1D Proteins) expression. Intriguingly, expression of SERPINB9 (show SERPINB9 Proteins), SERPINB1, and SERPINB4 (show SERPINB4 Proteins) is acquired during tumorigenesis in 29%, 29%, and 57% of the tumors

  3. Data suggest that serine protease inhibitor (SERPIN) B1 negatively regulates glioma cell migration and invasion probably by abrogating the expression of matrix metalloproteinase-2 and the activation of focal adhesion kinase.

  4. Decreased expression of SERPINB1 correlates with tumor invasion and poor prognosis in hepatocellular carcinoma.

  5. Apoptosis-inducing factor and leukocyte elastase inhibitor derived DNase II interact and can cooperate to induce cell death.

  6. Upon reactive center loop cleavage at Phe-343,SERPINB1 covalently complexes with GzmH (show GZMH Proteins). SERPINB1 overexpression suppresses GzmH (show GZMH Proteins)- or LAK (show ARL4C Proteins) cell-mediated cytotoxicity. Crystal structures show possible conformational changes in GzmH (show GZMH Proteins) for the suicide inhibition.

  7. In the resting state during human neutrophil extracellar trap generation, SerpinB1 is exclusively in the cytoplasm, consistent with the current understanding of clade B serpins, and it may migrate and regulate events in the cell nucleus.

  8. These results suggest that serpin B1 may be a novel marker of active ulcerative colitis and may play an important role in the pathogenesis of inflammatory bowel disease.

  9. serpinB1 sustains a healthy neutrophil reserve that is required in acute immune responses.

  10. The findings define an innate role for SerpinB1 in cystic fibrosis (show S100A8 Proteins) airways.

serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 (SERPINB1) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SERPINB1

  • serpin peptidase inhibitor, clade B (ovalbumin), member 1 (SERPINB1)
  • serpin peptidase inhibitor, clade B (ovalbumin), member 1 (serpinb1)
  • serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1 (serpinb1l1)
  • leukocyte elastase inhibitor-like (LOC100737407)
  • serine (or cysteine) peptidase inhibitor, clade B, member 1a (Serpinb1a)
  • 1190005M04Rik protein
  • AI325983 protein
  • EI protein
  • EIA protein
  • elanh2 protein
  • lei protein
  • m/nei protein
  • mnei protein
  • PI-2 protein
  • pi2 protein
  • serpinb1 protein
  • si:dkey-177p2.11 protein
  • si:dkey-177p2.12 protein
  • zgc:91981 protein

Protein level used designations for SERPINB1

serpin peptidase inhibitor, clade B (ovalbumin), member 1 , protease inhibitor 2, monocyte/neutrophil derived , serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1 , Leukocyte elastase inhibitor , leukocyte elastase inhibitor-like , leukocyte elastase inhibitor A , ovalbumin , serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1a , serine (or cysteine) proteinase inhibitor, clade B, member 1a , serine protease inhibitor EIA , serpin B1a , leukocyte elastase inhibitor , peptidase inhibitor 2 , protease inhibitor 2 (anti-elastase), monocyte/neutrophil derived , serpin B1 , LEI , leukocyte elastase inhibitor A-like protein , serpin peptidase inhibitor, clade B (ovalbumin), member 1 tv1

GENE ID SPECIES
282222 Bos taurus
420894 Gallus gallus
436926 Danio rerio
471841 Pan troglodytes
488191 Canis lupus familiaris
494155 Danio rerio
707471 Macaca mulatta
100389258 Callithrix jacchus
100446207 Pongo abelii
100596114 Nomascus leucogenys
100737407 Sus scrofa
66222 Mus musculus
1992 Homo sapiens
507264 Bos taurus
100049797 Equus caballus
100155145 Sus scrofa
734432 Xenopus laevis
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