SERPINB1 Protein (His tag)
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- Target See all SERPINB1 Proteins
- SERPINB1 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 (SERPINB1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This SERPINB1 protein is labelled with His tag.
- Purpose
- Recombinant Human SERPINB1/PI2 Protein (Human Cells, His Tag)
- Sequence
- Met 1-Pro379
- Characteristics
- Recombinant Human Serine Protease Inhibitor-clade B1 is produced by our Mammalian expression system and the target gene encoding Met1-Pro379 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SERPINB1 Protein
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serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 (SERPINB1) (AA 1-379) protein (GST tag)
SERPINB1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 (SERPINB1) (AA 201-300) protein (GST tag)SERPINB1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 (SERPINB1) (AA 1-379) protein (Strep Tag)Crystallography grade SERPINB1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 (SERPINB1) protein (Myc-DYKDDDDK Tag)SERPINB1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 (SERPINB1) (AA 1-379), (full length) protein (His-SUMO Tag)SERPINB1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- SERPINB1 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1 (SERPINB1))
- Alternative Name
- SERPINB1/PI2 (SERPINB1 Products)
- Synonyms
- ELANH2 Protein, zgc:91981 Protein, si:dkey-177p2.11 Protein, si:dkey-177p2.12 Protein, EI Protein, LEI Protein, M/NEI Protein, MNEI Protein, PI-2 Protein, PI2 Protein, elanh2 Protein, lei Protein, m/nei Protein, mnei Protein, pi2 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 1 Protein, serpin family B member 1 Protein, serpin family B member 1 L homeolog Protein, SERPINB1 Protein, serpinb1 Protein, serpinb1.L Protein
- Background
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Background: SERPINB1 is a member of the serpin family and Ov-serpin subfamily. As protease inhibitors, serpins have an array of functions including regulating blood coagulation, fibrinolysis, the complement pathway, angiogenesis, inflammation, tumor suppression, extracellular matrix remodeling, and cell motility. SERPINB1 regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Reactive bond 1 of SerpinB1 is specific for reaction with chymotrypsin-like protease such as cathepsin G, chymotrypsin or chymase. Reactive bond 2 of SerpinB1 is specific for reaction with elastase-like protease such as neutrophyl elastase, proteinase-3, pancreatic elastase or PSA. In addition, SERPINB1 also functions as a potent intracellular inhibitor of granzyme H.
Synonym: Leukocyte elastase inhibitor,SERPINB1, Monocyte/neutrophil elastase inhibitor, M/NEI, Peptidase inhibitor 2, PI-2, PI2, EI,ELANH2,HEL-S-27,HEL57,LEI,MNEI,
- Molecular Weight
- 43.8 kDa
- UniProt
- P30740
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