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serpin Peptidase Inhibitor, Clade H (Heat Shock Protein 47), Member 1, (Collagen Binding Protein 1) Proteins (SERPINH1)

SERPINH1 encodes a member of the serpin superfamily of serine proteinase inhibitors. Additionally we are shipping SERPINH1 Antibodies (137) and SERPINH1 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SERPINH1 12406 P19324
SERPINH1 871 P50454
SERPINH1 29345 P29457
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Top SERPINH1 Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag Human Serpin H1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%. 50 μg Log in to see 2 to 3 Days
$346.50
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Mammalian Cells Human His tag   50 μg Log in to see 5 Days
$522.50
Details
HOST_Human Human His tag   10 μg Log in to see 11 Days
$300.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,076.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,107.50
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,107.50
Details
HOST_HEK-293 Human His tag   0.05 mg Log in to see 2 to 3 Days
$618.75
Details

SERPINH1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , , , ,
,
Rat (Rattus)

Top referenced SERPINH1 Proteins

  1. Human SERPINH1 Protein expressed in HEK-293 Cells - ABIN2181754 : Hattori, Takahash, Yutani, Fujisawa, Nakanishi, Takigawa: Rheumatoid arthritis-related antigen 47kDa (RA-A47) is a product of colligin-2 and acts as a human HSP47. in Journal of bone and mineral metabolism 2001 (PubMed)
    Show all 2 references for ABIN2181754

More Proteins for serpin Peptidase Inhibitor, Clade H (Heat Shock Protein 47), Member 1, (Collagen Binding Protein 1) (SERPINH1) Interaction Partners

Mouse (Murine) serpin Peptidase Inhibitor, Clade H (Heat Shock Protein 47), Member 1, (Collagen Binding Protein 1) (SERPINH1) interaction partners

  1. HSP47 appears after a period of certain activities to repair damaged collagen fibers, and the activity was returned to a state of equilibrium at day 30 with significantly diminished expression. Thus, the results suggest that HSP47 is actively involved in homeostasis of periodontal tissue subjected to occlusal overload

  2. Intradermal administration of siHSP47-nanoparticles effectively reduced HSP47 protein expression in skin to normal level.

  3. 2014). Data show that the expression of heat shock protein 4 (show HSP47 Proteins)7 (HSP47) was increased in the scleroderma mouse model.

  4. Deletion of Hsp47 caused activated hepatic stellate cells to undergo ER stress-mediated apoptosis when autophagy was inhibited

  5. Mouse embryonic stem cell migration and differentiation into smooth muscle cells is induced by the over-expression of HSP47.

  6. Authors conclude that heat shock protein 47 (show HSP47 Proteins) plays an essential role in Schistosoma japonicum-induced hepatic fibrosis in mice.

  7. miR (show MLXIP Proteins)-29b down-regulates HSP47 and LOX (show LOX Proteins) expression.

  8. expression patterns of HSP70 (show HSP70 Proteins) and HSP47 in tissues following short-pulse laser irradiation

  9. The pH sensitivity of murine heat shock protein 47 (HSP47 (show HSP47 Proteins)) binding to collagen is affected by mutations in the breach histidine cluster.

  10. These results demonstrate that Hsp47 is indispensable for well-organized cartilage and normal endochondral bone formation.

Human serpin Peptidase Inhibitor, Clade H (Heat Shock Protein 47), Member 1, (Collagen Binding Protein 1) (SERPINH1) interaction partners

  1. The essential parts of the Golgi stress response from the perspective of the organelle autoregulation. The pathways of the mammalian Golgi stress response have been identified, specifically the HSP47 pathway.

  2. Overexpression of LOXL2 (show LOXL2 Proteins) and SERPINH1 was observed in clinical specimens of lung cancer and fibrotic lesions. Downregulation of miR (show MLXIP Proteins)-29a caused overexpression of LOXL2 (show LOXL2 Proteins) and SERPINH1 in lung cancer and IPF, suggesting that these genes are involved in the pathogenesis of these two diseases.

  3. The changes in the SERPINH1 and SERPINF1 (show SERPINF1 Proteins) genes in patients with osteogenesis imperfect were synonymous polymorphisms or missense changes located in non-coding regions.

  4. Overexpression of HSP47 is associated with poor prognosis in patients with esophageal squamous cell carcinoma and this is consistent with the function of HSP47 in terms of increased cell proliferation and colony formation.

  5. A novel homozygous variant in SERPINH1 associated with a severe, lethal presentation of osteogenesis imperfecta (show COL1A2 Proteins) with hydranencephaly.

  6. The present study demonstrates that HSP47 promotes glioma angiogenesis and highlights the importance of HSP47 as an attractive therapeutic target of GBM.

  7. Although the chemical chaperone 4-PBA partially restores the solubility of the Hsp47 OI mutants, collagen-binding activity of Hsp47 was not improved.

  8. Data show that the expression of heat shock protein 47 (HSP47 (show HSP47 Proteins)) was increased in the peripheral blood mononuclear cells and plasma from scleroderma patients.

  9. Mutations in the HSP47 and FKBP65 produce a moderately severe form of Osteogenesis imperfect.

  10. In patients with schistosomiasis japonica, TGF-beta1 (show TGFB1 Proteins) participates not only in the inflammatory process, but also in the fibrotic process in which Hsp47 and CTGF (show CTGF Proteins) probably play a key role.

SERPINH1 Protein Profile

Protein Summary

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

Gene names and symbols associated with SERPINH1

  • serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) (SERPINH1)
  • serine (or cysteine) peptidase inhibitor, clade H, member 1 (Serpinh1)
  • serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) (serpinh1)
  • serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) (Serpinh1)
  • astp3 protein
  • BERF-1 protein
  • cbp1 protein
  • cbp2 protein
  • colligin protein
  • DKFZp468B197 protein
  • gp46 protein
  • hsp47 protein
  • J6 protein
  • OI10 protein
  • pig14 protein
  • pprom protein
  • ra-a47 protein
  • SERPINH1 protein
  • serpinh2 protein

Protein level used designations for SERPINH1

serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) , serine (or cysteine) proteinase inhibitor, clade H, member 1 , Serpin H1 , serpin H1-like , 47 kDa heat shock protein , beta enolase repressor factor 1 , collagen binding protein 1 , collagen-binding protein , serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1 , serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2 , serine (or cysteine) proteinase inhibitor, clade H, member 2 , serine protease inhibitor J6 , serpin H1 , colligin , heat shock protein 47 , serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) , arsenic-transactivated protein 3 , cell proliferation-inducing gene 14 protein , colligin-1 , colligin-2 , rheumatoid arthritis antigen A-47 , rheumatoid arthritis-related antigen RA-A47 , serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2, (collagen-binding protein 2) , GP46 , collagen binding protein 2 , serine (or cysteine) peptidase inhibitor, clade H, member 1 , serine proteinase inhibitor, clade H (heat shock protein 47), member 1 , serpin peptidase inhibitor, clade H, member 1

GENE ID SPECIES
466899 Pan troglodytes
696171 Macaca mulatta
100064560 Equus caballus
100172353 Pongo abelii
100400076 Callithrix jacchus
100597132 Nomascus leucogenys
12406 Mus musculus
396228 Gallus gallus
871 Homo sapiens
100158395 Xenopus laevis
485187 Canis lupus familiaris
510850 Bos taurus
29345 Rattus norvegicus
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