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anti-tau Tubulin Kinase 1 (Ttbk1) Antibodies

Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Additionally we are shipping tau Tubulin Kinase 1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Ttbk1 84630 Q5TCY1
Ttbk1 106763 Q6PCN3
Ttbk1 316229  
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Top anti-tau Tubulin Kinase 1 Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of TTBK1 in mouse brain tissue with this product at 2.5 μg/ml. Western blot analysis of TTBK1 in Jurkat lysate with this product at 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB TTBK1 Antibody (Center) (ABIN1881954) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the TTBK1 antibody detected the TTBK1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB TTBK1 Antibody (N-term) (ABIN1881955) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TTBK1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. TTBK1 Antibody (N-term) (ABIN1881955) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TTBK1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details

Ttbk1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) ,


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Top referenced anti-tau Tubulin Kinase 1 Antibodies

  1. Human Polyclonal Ttbk1 Primary Antibody for WB - ABIN1881954 : Sato, Xu, Okuyama, Martinez, Walsh, Jacobsen, Swan, Schlautman, Ciborowski, Ikezu: Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 (PubMed)
    Show all 2 references for ABIN1881954

  2. Human Polyclonal Ttbk1 Primary Antibody for EIA, IHC (p) - ABIN501089 : Sato, Cerny, Buescher, Ikezu: Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation. in Journal of neurochemistry 2006 (PubMed)

More Antibodies against tau Tubulin Kinase 1 Interaction Partners

Human tau Tubulin Kinase 1 (Ttbk1) interaction partners

  1. TTBK1/2 kinases may represent attractive targets for therapeutic intervention for TDP-43 (show TARDBP Antibodies) proteinopathies such as Amyotrophic lateral sclerosis and Frontotemporal lobar degeneration-TDP.

  2. X-ray diffraction data were collected and the structure of TTBK1 was determined by molecular replacement both as an apo (show C9orf3 Antibodies) structure and in complex with a kinase inhibitor

  3. The study suggested that a role for TTBK1 in pre-tangle formation prior to the formation of fibrillar tau and strengthen the idea that tau is phosphorylated at Ser422 at an early/intermediate stage in NFT formation.

  4. TTBK1 may play an important role in the pathogenesis of sporadic late-onset Alzheimer's disease in a Han Chinese population.

  5. This study demonistrated that TTBK1 is a promising new candidate tau phosphorylation-related gene for Alzheimer's disease risk.

  6. TTBK1 in AD brain may be one of the underlying mechanisms inducing CDK5 (show CDK5 Antibodies) and calpain activation, NR2B (show GRIN2B Antibodies) downregulation, and subsequent memory dysfunction.

Mouse (Murine) tau Tubulin Kinase 1 (Ttbk1) interaction partners

  1. TTBK1 accelerates motor neuron neurodegeneration by recruiting proinflammatory monocytes and enhancing sensitivity to neurotoxicity in inflammatory conditions.

  2. TTBK1 up-regulation enhances tau phosphorylation and oligomerization, whose toxicity results in enhanced neurodegeneration and locomotor dysfunction in a tauopathy animal model.

tau Tubulin Kinase 1 (Ttbk1) Antigen Profile

Protein Summary

Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU.

Gene names and symbols associated with Ttbk1

  • tau tubulin kinase 1 (TTBK1) antibody
  • tau tubulin kinase 1 (Ttbk1) antibody
  • AU017937 antibody
  • AW048023 antibody
  • BDTK antibody
  • C330008L01Rik antibody
  • RGD1559518 antibody

Protein level used designations for Ttbk1

tau-tubulin kinase 1 , brain-derived tau kinase

GENE ID SPECIES
416713 Gallus gallus
84630 Homo sapiens
106763 Mus musculus
100684678 Canis lupus familiaris
100155509 Sus scrofa
786439 Bos taurus
316229 Rattus norvegicus
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