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tyrosyl-tRNA Synthetase 2, Mitochondrial Proteins (YARS2)

YARS2 encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Additionally we are shipping tyrosyl-tRNA Synthetase 2, Mitochondrial Antibodies (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse YARS2 YARS2 70120 Q8BYL4
Rat YARS2 YARS2 287924 Q5I0L3
YARS2 51067 Q9Y2Z4
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Top tyrosyl-tRNA Synthetase 2, Mitochondrial Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 20 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

YARS2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

Top referenced tyrosyl-tRNA Synthetase 2, Mitochondrial Proteins

  1. Human YARS2 Protein expressed in Escherichia coli (E. coli) - ABIN1098625 : Bonnefond, Fender, Rudinger-Thirion, Giegé, Florentz, Sissler: Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS. in Biochemistry 2005 (PubMed)
    Show all 2 references for ABIN1098625

More Proteins for tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2) Interaction Partners

Human tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2) interaction partners

  1. Data identified novel YARS2 mutations and noted marked phenotypic variability among YARS2 MLASA patients, with phenotypes ranging from mild to lethal, suggesting that the background mtDNA haplotype may be contributing to the phenotypic variability.

  2. The study confirms mutations in YARS2 as a cause of MLASA and shows that, like some of the cytoplasmic ARSs, mitochondrial ARSs occur in high-molecular-weight complexes.

  3. first example of a TyrRS (show Yars Proteins) lacking specificity toward N1-N72 and thus of a TyrRS (show Yars Proteins) disobeying the identity rules

  4. The YARS2 mutation reported here is an alternative cause of MLASA.

  5. The gene for mitochondrial tyrosyl-tRNA synthetase (show Yars Proteins) is described and the initial characterization of the enzyme is reported. Genes for the remaining missing synthetases have also been found with the exception of human glutaminyl-tRNA synthetase (show EPRS Proteins).

  6. the structure of a strictly mitochondrial human synthetase, namely tyrosyl-tRNA synthetase (mt-TyrRS), in complex with an adenylate analog at 2.2 A resolution

tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2) Protein Profile

Protein Summary

This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2).

Gene names and symbols associated with YARS2

  • tyrosyl-tRNA synthetase 2 (mitochondrial) (Yars2)
  • tyrosyl-tRNA synthetase 2, mitochondrial (YARS2)
  • 2210023C10Rik protein
  • CGI-04 protein
  • MLASA2 protein
  • MT-TYRRS protein
  • RGD1311696 protein
  • TYRRS protein

Protein level used designations for YARS2

tyrosine--tRNA ligase, mitochondrial , tyrRS , tyrosyl-tRNA synthetase, mitochondrial , tyrosine tRNA ligase 2, mitochondrial

GENE ID SPECIES
70120 Mus musculus
287924 Rattus norvegicus
51067 Homo sapiens
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