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anti-Human MAS1 Antibodies:
anti-Mouse (Murine) MAS1 Antibodies:
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Human Polyclonal MAS1 Primary Antibody for ICC, IF - ABIN270653
Bosnyak, Widdop, Denton, Jones: Differential mechanisms of ang (1-7)-mediated vasodepressor effect in adult and aged candesartan-treated rats. in International journal of hypertension 2011
Show all 3 references for ABIN270653
Human Polyclonal MAS1 Primary Antibody for ICC, IF - ABIN4332754
da Silveira, Coelho, Vieira, Sachs, Barroso, Costa, Bretas, Bader, de Sousa, da Silva, dos Santos, Simões e Silva, Teixeira: Anti-inflammatory effects of the activation of the angiotensin-(1-7) receptor, MAS, in experimental models of arthritis. in Journal of immunology (Baltimore, Md. : 1950) 2010
Show all 3 references for ABIN4332754
Human Polyclonal MAS1 Primary Antibody for IHC, WB - ABIN2784455
Santos, Simoes e Silva, Maric, Silva, Machado, de Buhr, Heringer-Walther, Pinheiro, Lopes, Bader, Mendes, Lemos, Campagnole-Santos, Schultheiss, Speth, Walther: Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. in Proceedings of the National Academy of Sciences of the United States of America 2003
The objective of this study was to characterize the profiles of Ang-(1-7), MAS receptor, ACE(2), NEP and PEP during the ovulatory process in cattle.
These results indicated that angiotensin-(1-7)/ACE2 (show ACE2 Antibodies)/Mas axis may reduce liver lipid accumulation partly by regulating lipid-metabolizing genes through ATP/P2 receptor/CaM (show CALM1 Antibodies) signaling pathway.
Ang-(1 (show ANGPT1 Antibodies)-7) downregulated AT1R (show AGTR1 Antibodies) mRNA, upregulated mRNA levels of Ang II (show AGT Antibodies) type 2 receptor (AT2R (show AGTR2 Antibodies)) and Mas receptor (MasR) and p38-MAPK (show MAPK14 Antibodies) phosphorylation and suppressed H22 cell-endothelial cell communication
MAS1 might act as an inhibitory regulator of breast cancer.
Data show that MAS receptor exhibited constitutive activity that was inhibited by the non-peptide inverse agonist.
Data suggest that angiotensin converting enzyme 2 (show ACE2 Antibodies)/angiotensin II-(1-7)/MAS1 axis regulates leukocyte recruitment/activation, cell proliferation, and inflammation/fibrosis; main topic here is kidney/inflammatory renal disease. [REVIEW]
Up-regulation of the ACE2 (show ACE2 Antibodies)/Ang-(1 (show ANGPT1 Antibodies)-7)/Mas axis protected against pulmonary fibrosis by inhibiting the MAPK (show MAPK1 Antibodies)/NF-kappaB (show NFKB1 Antibodies) pathway.
A proximal promoter construct for the MAS gene was repressed by the SOX (show PIPOX Antibodies) [SRY (show SRY Antibodies) (sex-determining region on the Y chromosome) box] proteins SRY (show SRY Antibodies), SOX2 (show SOX2 Antibodies), SOX3 (show SOX3 Antibodies) and SOX14 (show SOX14 Antibodies), of which SRY (show SRY Antibodies) is known to interact with the KRAB domain.
Mas appears to be a critical component required for NO-mediated vasodilatation induced by renin angiotensin system-dependent and RAS-independent agonists and therefore arises as a key pharmacological target to modulate endothelial function
Control of adipogenesis by the autocrine interplays between angiotensin 1-7/Mas receptor and angiotensin II/AT1 receptor (show AGTRAP Antibodies) signaling pathways.
MasR was significantly upregulated in colon adenocarcinoma compared with non-neoplastic colon mucosa, which showed little or no expression of it. ACE (show ACE Antibodies) gene expression and enzymatic activity were also increased in the tumors.
Ang-(1 (show ANGPT1 Antibodies)-7)/Mas axis seems more important in autonomic modulation of arterial pressure than heart rate.
Mas receptor mediates cardioprotection of angiotensin-(1-7) against Ang II (show AGT Antibodies)-induced cardiomyocyte autophagy and cardiac remodelling through inhibition of oxidative stress.
MAS receptors mediate vasoprotective and atheroprotective effects of candesartan upon the recovery of vascular ACE2 (show ACE2 Antibodies)-angiotensin-(1-7)-MAS axis functionality
Mas receptor deficiency results in exacerbated inflammation in LPS (show TLR4 Antibodies)-challenged mice, which suggest a potential role for the Mas receptor as a regulator of systemic and brain inflammatory response induced by LPS (show TLR4 Antibodies).
a Mas receptor-mediated mechanism may stimulate pancreatic cell development
Hydronephrosis led to an increase of ACE (show ACE Antibodies) level and a decrease of ACE2 (show ACE2 Antibodies) and Mas receptor in the heart.
TGF-beta (show TGFB1 Antibodies) inhibits Mas receptor expression in fibroblasts but not in myoblasts or differentiated myotubes in animal model of muscular distrophy.
Deletion of the MasR causes marked increase in the aortic intima:media ratio, which is not due to generalized cellular proliferation.
The complete mouse Mas gene structure and organization.
Participation of AT1 (show SLC33A1 Antibodies) and Mas receptors in the modulation of inflammatory pain.
oncogene\; may be involved in function or development of neural tissues
, proto-oncogene Mas
, MAS proto-oncogene
, angiotensin-(1-7) receptor