Browse our Renin Proteins (REN)

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Renin Proteins (REN)
On are 34 Renin (REN) Proteins from 11 different suppliers available. Additionally we are shipping Renin Antibodies (120) and Renin Kits (82) and many more products for this protein. A total of 247 Renin products are currently listed.
AF465352, HNFJ2, RATRENAA, Ren, Ren1, RENAA
list all proteins Gene Name GeneID UniProt
REN 216858 Q8K485
REN 24715 P08424
REN 5972 P00797

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Renin Proteins (REN) by Origin

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Top referenced Renin Proteins

  1. Mouse (Murine) Renin Protein expressed in Human Cells - ABIN2007609 : Imai, Miyazaki, Hirose, Hori, Hayashi, Kageyama, Ohkubo, Nakanishi, Murakami: Cloning and sequence analysis of cDNA for human renin precursor. in Proceedings of the National Academy of Sciences of the United States of America 1984 (PubMed)
    Show all 3 references for 2007609

  2. Human Renin Protein expressed in Human Cells - ABIN2003666 : Nguyen, Delarue, Burcklé, Bouzhir, Giller, Sraer: Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. in The Journal of clinical investigation 2002 (PubMed)
    Show all 3 references for 2003666

  3. Mouse (Murine) Renin Protein expressed in HEK-293 Cells - ABIN2181693 : Adams, Beveridge, van der Weyden, Mangs, Leedman, Morris: HADHB, HuR, and CP1 bind to the distal 3'-untranslated region of human renin mRNA and differentially modulate renin expression. in The Journal of biological chemistry 2003 (PubMed)

More Proteins for Renin Interaction Partners

Mouse (Murine) Renin (REN) interaction partners

  1. Results show negative regulation of HDAC1 (show HDAC1 Proteins) by a Cul3 (show CUL3 Proteins)-REN E3 ubiquitin ligase (show MUL1 Proteins) complex.

  2. REN is upregulated by neurogenic signals (retinoic acid, EGF, and NGF) in embryonal stem (ES) cells and neural progenitor cell lines in association with neurotypic differentiation.

  3. REN protein enhances caspase-3 (show CASP3 Proteins) activation and antagonizes the Shh (show SHH Proteins) pathway suggesting that this gene may represent a restraint of Shh (show SHH Proteins) signaling.

Human Renin (REN) interaction partners

  1. Prospective study of consecutive cardiac disease patients referred for cardiac catheterization has revealed distinct cardiac disease condition-associated differences in the frequencies of elevations in plasma renin, plasma aldosterone concentration, and the aldosterone-renin ratio

  2. Renin-angiotensin system transgenic mouse model suggests that renal injury in preeclampsia may be mediated through local VEGF.

  3. Data suggest mild primary aldosteronism (PA), where plasma renin activity is not as suppressed, is susceptible to dietary sodium influences on renin and ARR (show SAG Proteins) (aldosterone to renin ratio). Optimal screening for PA should occur under conditions of high dietary sodium intake (rather than condition of low dietary sodium intake as frequently prescribed for patients with hypertension, which may be a symptom of PA).

  4. This study demonstrates the efficacy of aldosterone/direct renin concentration ratio as a screening test for primary aldosteronism.

  5. The dominant model (CC vs. CT+TT) of rs1894111 polymorphism in the ADRBK1 gene might be associated with low-renin hypertension in Han Chinese.

  6. Data show that the optimum time for beta-adrenoreceptor antagonists (beta-blockers) withdrawal was 2 weeks when using direct renin concentration (DRC (show FECH Proteins)) and 3 weeks for plasma renin activity (PRA (show S100A6 Proteins)).

  7. Active renin was not significantly different between hypertensive patients with and without left ventricular hypertrophy.

  8. The present study provides evidence that the rs1464816 polymorphism in REN is associated with CKD progression in ADPKD.

  9. Plasma renin and Aldosterone to renin ratio but not aldosterone are independently associated with presence of carotid plaques in coronary artery disease patients.

  10. concentrations of serum aldosterone, plasma direct renin, and plasma renin activity were measured after a night's rest and again after walking for two hours.

Renin (REN) Protein Profile

Protein Summary

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.

Alternative names and synonyms associated with Renin (REN)

  • renin-like (LOC100054248)
  • renin (REN)
  • potassium channel tetramerisation domain containing 11 (Kctd11)
  • renin (Ren)
  • renin-like (LOC100524822)
  • AF465352 protein
  • HNFJ2 protein
  • RATRENAA protein
  • Ren protein
  • Ren1 protein
  • RENAA protein

Protein level used designations for Renin Proteins (REN)

angiotensinogenase , prorenin , BTB/POZ domain-containing protein KCTD11 , retinoic acid, EGF, and NGF upregulated , renin 1 structural , angiotensin-forming enzyme , renin precursor, renal , renin-like , preprorenin , Angiotensinogenase

100054248 Equus caballus
469651 Pan troglodytes
574299 Macaca mulatta
216858 Mus musculus
24715 Rattus norvegicus
5972 Homo sapiens
403838 Canis lupus familiaris
100724037 Cavia porcellus
280909 Bos taurus
443310 Ovis aries
431167 Gallus gallus
100399036 Callithrix jacchus
100524822 Sus scrofa
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