Browse our SIN3A Proteins (SIN3A)

Full name:
SIN3 Transcription Regulator Homolog A (Yeast) Proteins (SIN3A)
On are 4 SIN3 Transcription Regulator Homolog A (Yeast) (SIN3A) Proteins from 2 different suppliers available. Additionally we are shipping SIN3A Antibodies (56) and and many more products for this protein. A total of 65 SIN3A products are currently listed.
AW553200, mKIAA4126, mSin3A, Sin3
list all proteins Gene Name GeneID UniProt
SIN3A 25942 Q96ST3
Rat SIN3A SIN3A 363067  
SIN3A 20466 Q60520

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SIN3A Proteins (SIN3A) by Origin

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More Proteins for SIN3A Interaction Partners

Human SIN3 Transcription Regulator Homolog A (Yeast) (SIN3A) interaction partners

  1. Haploinsufficiency of SIN3A causes mild intellectual disability by affecting the development of cortical integrity.

  2. Two novel translocations leading to the inactivation of RUNX1 (show RUNX1 Proteins) and its partners SIN3A and TCF12 (show TCF12 Proteins) in myeloid leukemia (show BCL11A Proteins).

  3. Study suggests a lack of association of SIN3A gene sequence variants with azoospermia caused by Sertoli cell-only syndrome in humans.

  4. down regulation of miR (show MLXIP Proteins)-202 increased the expression of its target Mxd1 (show MXD1 Proteins), followed by Mxd1 (show MXD1 Proteins) recruitment to the Sin3A repressor complex and through its dimerization with Max, and increased repression of Myc (show MYC Proteins)-Max target proteins.

  5. protein pairs significantly correlated with an increased risk of death in non-small cell lung cancer: mSin3A with p16, and c-Myc (show MYC Proteins) with mSinA

  6. Aberrantly expressed miR (show MLXIP Proteins)-210 regulates human U251 glioma cells apoptosis and proliferation partly through directly down-regulating SIN3A protein expression.

  7. Bone-marrow-specific deletion of Sin3a, indicated that Sin3a-associated HDAC1/2-activity is essential for hematopoietic stem cell homeostasis.

  8. SIN3A, generally regarded as a transcriptional repressor, is required for induction of gene transcription by the aryl hydrocarbon receptor (show AHR Proteins).

  9. EBNA3C binds strongly to BATF/IRF4/SPI1/RUNX3 sites to enhance transcription and recruits RBPJ/Sin3A- and REST/NRSF-repressive complexes to repress p14(ARF) and p16(INK4A) expression

  10. BIM (show BCL2L11 Proteins) silencing in anaplastic large cell lymphoma occurs through recruitment of MeCP2 (show MECP2 Proteins) and the SIN3a/histone deacetylase 1/2 corepressor complex.

Mouse (Murine) SIN3 Transcription Regulator Homolog A (Yeast) (SIN3A) interaction partners

  1. Taken together, Fam60a is an essential core subunit of a variant Sin3a-Hdac (show HDAC3 Proteins) complex in embryonic stem cells that is required to promote rapid proliferation and prevent unscheduled differentiation.

  2. TGF-beta1 (show TGFB1 Proteins)-induced inhibition of PPARgamma (show PPARG Proteins) transcription depends on formation of a functional transcriptional regulatory complex that includes Smad3 (show SMAD3 Proteins), mSin3A and HDAC1 (show HDAC1 Proteins) at the PPARgamma (show PPARG Proteins) promoter.

  3. Sin3a mRNA is recruited during maturation and that inhibiting its recruitment not only inhibits development beyond the 2-cell stage but also compromises the fidelity of reprogramming gene expression

  4. Report role of myocardial mSin3A/HDAC1 (show HDAC1 Proteins)/2 complex in mediating the beneficial effects of exercise in diabetic cardiomyopathy.

  5. SIN3A, generally regarded as a transcriptional repressor, is required for induction of gene transcription by the aryl hydrocarbon receptor (show AHR Proteins).

  6. Treatment with GlcN, in contrast, inhibits LPS (show TLR4 Proteins)-ind inflammation and decreased LPS (show TLR4 Proteins)-mediated recruitment of OGT (show OGT Proteins), mSin3A, and HDACs.

  7. Within the male germline, Sin3a is required for the mitotic reentry of gonocytes, but is dispensable for the maintenance of differentiating spermatogonia and subsequent spermatogenic processes.

  8. Sin3A-deleted testes exhibit a Sertoli-cell only phenotype, consistent with the absolute requirement for Sin3A in germ cells' development and/or viability.

  9. Sin3 has an important role in the regulation of cell cycle kinetics of the myogenic progenitor cell population

  10. ARID4B physically interacts with the breast cancer metastasis suppressor BRMS1 (show BRMS1 Proteins), and we detected differential binding of the Arid4b alleles to mSIN3A and mSDS3 (show SUDS3 Proteins)

SIN3A Protein Profile

Protein Summary

The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex.

Alternative names and synonyms associated with SIN3A

  • SIN3 transcription regulator homolog A (yeast) (SIN3A)
  • SIN3 homolog A, transcription regulator (yeast) (SIN3A)
  • SIN3 transcription regulator family member A (SIN3A)
  • SIN3 transcription regulator homolog A (yeast) (Sin3a)
  • transcriptional regulator, SIN3A (yeast) (Sin3a)
  • AW553200 protein
  • mKIAA4126 protein
  • mSin3A protein
  • Sin3 protein

Protein level used designations for SIN3A

SIN3 homolog A, transcription regulator , transcriptional co-repressor Sin3A , paired amphipathic helix protein Sin3a , SIN3 homolog A, transcription regulator (yeast) , paired amphipathic helix protein Sin3a-like , SIN3 transcription regulator homolog A , histone deacetylase complex subunit Sin3a , transcriptional corepressor Sin3a , transcriptional regulator, SIN3A , transcriptional regulator, SIN3 yeast homolog A

453759 Pan troglodytes
478372 Canis lupus familiaris
518504 Bos taurus
705719 Macaca mulatta
100404916 Callithrix jacchus
100477344 Ailuropoda melanoleuca
100641919 Amphimedon queenslandica
25942 Homo sapiens
415307 Gallus gallus
363067 Rattus norvegicus
20466 Mus musculus
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