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Browse our anti-PFKFB3 (PFKFB3) Antibodies

Full name:
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 Antibodies (PFKFB3)
On www.antibodies-online.com are 80 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) Antibodies from 15 different suppliers available. Additionally we are shipping PFKFB3 Proteins (11) and PFKFB3 Kits (4) and many more products for this protein. A total of 102 PFKFB3 products are currently listed.
Synonyms:
6-biphosphatase, 6-bisphosphatase, 6-phosphofructo-2-kinase/fructose-2, 6PF-2-K/Fru-2, E330010H22Rik, iPFK-2, IPFK2, PFK2, PFKFB3, uPFK-2, wu:fc31e01, zgc:73257
list all antibodies Gene Name GeneID UniProt
PFKFB3 5209 Q16875
PFKFB3 170768  
PFKFB3 117276 O35552

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Most Popular Reactivities for anti-PFKFB3 (PFKFB3) Antibodies

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anti-Human PFKFB3 Antibodies:

anti-Mouse (Murine) PFKFB3 Antibodies:

anti-Rat (Rattus) PFKFB3 Antibodies:

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Top referenced anti-PFKFB3 Antibodies

  1. Human Polyclonal PFKFB3 Primary Antibody for EIA, IHC (p) - ABIN360653 : Navarro-Sabaté, Manzano, Riera, Rosa, Ventura, Bartrons: The human ubiquitous 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene (PFKFB3): promoter characterization and genomic structure. in Gene 2001 (PubMed)
    Show all 5 references for ABIN360653

  2. Human Polyclonal PFKFB3 Primary Antibody for IHC (p), WB - ABIN392768 : Telang, Yalcin, Clem, Bucala, Lane, Eaton, Chesney: Ras transformation requires metabolic control by 6-phosphofructo-2-kinase. in Oncogene 2006 (PubMed)
    Show all 4 references for ABIN392768

  3. Human Monoclonal PFKFB3 Primary Antibody for IP, ELISA - ABIN518808 : Bao, Mukai, Hishiki, Kubo, Ohmura, Sugiura, Matsuura, Nagahata, Hayakawa, Yamamoto, Fukuda, Saya, Suematsu, Minamishima: Energy management by enhanced glycolysis in G1-phase in human colon cancer cells in vitro and in vivo. in Molecular cancer research : MCR 2013 (PubMed)
    Show all 3 references for ABIN518808

  4. Human Polyclonal PFKFB3 Primary Antibody for IP, WB - ABIN948248 : Mendoza, Pocceschi, Kong, Leeper, Caro, Limesand, Burd: Control of Glycolytic Flux by AMP-Activated Protein Kinase in Tumor Cells Adapted to Low pH. in Translational oncology 2012 (PubMed)

  5. Human Polyclonal PFKFB3 Primary Antibody for WB - ABIN518807 : Yamamoto, Takano, Ishiwata, Ohmura, Nagahata, Matsuura, Kamata, Sakamoto, Nakanishi, Kubo, Hishiki, Suematsu: Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway. in Nature communications 2014 (PubMed)

  6. Human Polyclonal PFKFB3 Primary Antibody for IF (p), IHC (p) - ABIN744728 : Fu, Shi, Westaway, Jhamandas: Bioenergetic mechanisms in astrocytes may contribute to amyloid plaque deposition and toxicity. in The Journal of biological chemistry 2015 (PubMed)

More Antibodies against PFKFB3 Interaction Partners

Zebrafish 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) interaction partners

  1. Study showed that endothelial cells (ECs)relied on glycolysis rather than on oxidative phosphorylation for ATP production and that loss of the glycolytic activator PFKFB3 in ECs impaired vessel formation.

Human 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) interaction partners

  1. Our data suggest that chronic inflammation promotes the development of CRC (show CALR Antibodies) by stimulating aerobic glycolysis and IL-6 (show IL6 Antibodies) is functioning, at least partly, through regulating PFKFB3 at early stage of colorectal cancer (CRC (show CALR Antibodies)).

  2. MicroRNA-26b inhibits osteosarcoma cell migration and invasion by down-regulating PFKFB3 expression

  3. The expression of PFKFB3, PFKFB4 (show PFKFB4 Antibodies), NAMPT (show NAMPT Antibodies), and TSPAN13 (show TSPAN13 Antibodies) is strongly up-regulated in pediatric glioma.

  4. Data indicate that 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase3 (PFKFB3) and phosphofructokinase (PFK1 (show PFKM Antibodies)) expression allows discrimination between induced pluripotent stem cells (iPS (show SLC27A4 Antibodies)) and cancer stem cells (CSCs).

  5. Insulin (show INS Antibodies) resistance in obese boys leads to up-regulation of INSIG2 (show INSIG2 Antibodies) gene expression as well as to down-regulation of PFKFB1 (show PFKFB1 Antibodies), PFKFB3, and HK2 (show HK2 Antibodies) genes in the blood cells as compared to obese patients with normal insulin (show INS Antibodies) sensitivity.

  6. A binding site for miR (show MLXIP Antibodies)-26b was predicted in the 3'UTR (show UTS2R Antibodies) of PFKFB3. miR (show MLXIP Antibodies)-26b overexpression repressed PFKFB3 mRNA and protein levels.

  7. Data show that inhibition of AMP (show APRT Antibodies)-Activated kinase (AMPK (show PRKAA1 Antibodies)) or 6-phosphofructo-2-kinase-fructose-2,6-biphosphatase 3 (PFKFB3) results in enhanced cell death in mitosis.

  8. Shh (show SHH Antibodies) regulates PFKFB3 activation in breast cancer cells.

  9. study demonstrated that miR (show MLXIP Antibodies)-206 regulated PFKFB3 expression in breast cancer cells, thereby stunting glycolysis, cell proliferation and migration

  10. PFKFB3 promotes cell cycle progression and suppresses apoptosis via Cdk1 (show CDK1 Antibodies)-mediated phosphorylation of p27 (show PAK2 Antibodies).

Mouse (Murine) 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) interaction partners

  1. overexpression of PFKFB3 in HEK293 cells potentiated insulin (show INS Antibodies)-dependent phosphorylation of Akt (show AKT1 Antibodies) and Akt (show AKT1 Antibodies) substrates

  2. Data show that inhibition of AMP (show TMPRSS5 Antibodies)-Activated kinase (AMPK (show PRKAA1 Antibodies)) or 6-phosphofructo-2-kinase-fructose-2,6-biphosphatase 3 (PFKFB3) results in enhanced cell death in mitosis.

  3. Shear stress-mediated repression of endothelial cell metabolism via KLF2 (show KLF2 Antibodies) and PFKFB3 controls endothelial cell phenotype.

  4. PFKFB3 is a promising target for the reduction of endothelial glycolysis and its related pathological angiogenesis

  5. PFKFB3/iPFK2 responds to re-feeding, which in turn stimulates hypothalamic glycolysis and decreases hypothalamic AMPK (show PRKAA1 Antibodies) phosphorylation and alters neuropeptide expression in a pattern that is associated with suppression of food intake.

  6. High-fat diet feeding stimulates intestine 6-phosphofructo-2-kinase expression and induces intestine inflammatory response.

  7. Study showed that endothelial cells (ECs)relied on glycolysis rather than on oxidative phosphorylation for ATP production and that loss of the glycolytic activator PFKFB3 in ECs impaired vessel formation.

  8. a unique role for PFKFB3/iPFK2 in adipocytes with regard to diet-induced inflammatory responses in both adipose and liver tissues.

  9. inducible PFKFB3 is required for increased growth, metabolic activity and is regulated through active JAK2 (show JAK2 Antibodies) and STAT5 (show STAT5A Antibodies).

  10. Cooperation of adenosine with macrophage Toll (show TLR4 Antibodies)-4 receptor agonists leads to increased glycolytic flux through the enhanced expression of PFKFB3 gene.

PFKFB3 Antigen Profile

Antigen Summary

Synthesis and degradation of fructose 2,6-bisphosphate (By similarity).

Alternative names and synonyms associated with PFKFB3

  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) antibody
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (pfkfb3) antibody
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PTRG_09894) antibody
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (f263) antibody
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PGTG_20206) antibody
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (Tsp_06710) antibody
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (Pfkfb3) antibody
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (PFKFB4) antibody
  • 6-biphosphatase antibody
  • 6-bisphosphatase antibody
  • 6-phosphofructo-2-kinase/fructose-2 antibody
  • 6PF-2-K/Fru-2 antibody
  • E330010H22Rik antibody
  • iPFK-2 antibody
  • IPFK2 antibody
  • PFK2 antibody
  • PFKFB3 antibody
  • uPFK-2 antibody
  • wu:fc31e01 antibody
  • zgc:73257 antibody

Protein level used designations for PFKFB3

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 , 6-phosphofructo-2-kinase , fructose-2,6-biphosphatase 3 , 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 , 6PF-2-K/Fru-2,6-P2ASE brain/placenta-type isozyme , 6PF-2-K/Fru-2,6-P2ase 3 , PFK/FBPase 3 , 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3-like , 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase , 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase , 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme , fructose-6-phosphate,2-kinase/fructose-2, 6-bisphosphatase , iPFK-2 , inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase , renal carcinoma antigen NY-REN-56 , inducible 6-phosphofructo-2-kinase , 6PF-2-K/Fru-2,6-P2ASE brain-type isozyme , RB2K , 6-P2ase liver isozyme , 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase , 6PF-2-K/Fru-2,6-P2ase liver isozyme , PFK/FBPase

GENE ID SPECIES
418247 Gallus gallus
431861 Xenopus laevis
487139 Canis lupus familiaris
554477 Danio rerio
713062 Macaca mulatta
738397 Pan troglodytes
6348191 Pyrenophora tritici-repentis Pt-1C-BFP
100172898 Pongo abelii
100216216 Xenopus (Silurana) tropicalis
100350534 Oryctolagus cuniculus
100380757 Salmo salar
100414163 Callithrix jacchus
100464074 Ailuropoda melanoleuca
10535908 Puccinia graminis f. sp. tritici CRL 75-36-700-3
10911737 Trichinella spiralis
100070251 Equus caballus
5209 Homo sapiens
170768 Mus musculus
117276 Rattus norvegicus
407183 Bos taurus
415906 Gallus gallus
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