Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (Isoform alpha) antibody

Details for Product No. ABIN1042658, Supplier: Log in to see
Antigen
  • pp2ac
  • Ppp2ca
  • zgc:110641
  • PP2A
  • R75353
  • PP2Ac
  • PP2CA
  • PP2Calpha
  • RP-C
  • Pp2a1
  • PPP2CA
  • protein phosphatase 2, catalytic subunit, alpha isozyme
  • zgc:56064
  • protein phosphatase 2, catalytic subunit, beta isozyme
  • protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
  • ppp2ca
  • zgc:56064
  • ppp2cb
  • PPP2CA
  • Ppp2ca
  • PPP2CB
Alternatives
anti-Human Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme antibody for Immunofluorescence (fixed cells)
Epitope
Isoform alpha
19
18
13
11
9
7
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
126
103
80
17
13
11
9
7
6
5
5
4
3
3
3
1
1
1
1
1
Host
Mouse
112
22
4
4
3
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
5
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunoprecipitation (IP), Western Blotting (WB)
123
47
33
27
17
14
13
7
2
2
1
Options
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Immunogen Peptide from rat PP2A isoform alpha
Clone 2G9
Isotype IgG1
Specificity Rcognizes very well isoforms alpha and rat delta, weakly the human beta isoform, very weakly the rabbit gamma isoform
Cross-Reactivity Xenopus laevis, Rabbit, Chicken, Pig (Porcine)
Cross-Reactivity (Details) Human, Mouse, Rat. Predicted to react with Porcine, Rabbit, Chicken, Xenopus
Purification Protein G
Alternative Name PP2A alpha (PPP2CA Antibody Abstract)
Background Synonyms:
B/PR55, B/PR55 alpha, PP2A alpha antibody,PP2A C antibody,PP2A-alpha antibody,PP2AA_HUMAN antibody,PP2Ac antibody,PP2CA antibody
Gene ID 5515, 19052, 24672
OMIM 176915
UniProt P63331
Research Area Signaling, Kinases/Phosphatases
Pathways PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline try up to 1:1,000 for western blot
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
 image for anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (Isoform alpha) antibody (ABIN1042658) anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (Isoform alpha) antibody
Product cited in: Sontag, Nunbhakdi-Craig, Sontag, Diaz-Arrastia, Ogris, Dayal, Lentz, Arning, Bottiglieri: "Protein phosphatase 2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 11, pp. 2751-9, 2007 (PubMed).

Sontag, Hladik, Montgomery, Luangpirom, Mudrak, Ogris, White: "Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis." in: Journal of neuropathology and experimental neurology, Vol. 63, Issue 10, pp. 1080-91, 2004 (PubMed).