RPA3 antibody (AA 1-119) (Biotin)

Catalog No. ABIN1046034

Product Details anti-RPA3 Antibody (Biotin)

Target: RPA3 (Replication Protein A3, 14kDa (RPA3))

Binding Specificity: AA 1-119

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPA3 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Replication protein A 14 kDa subunit protein (1-119AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid freeze and thaw cycles.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RPA3

Target: RPA3 (Replication Protein A3, 14kDa (RPA3))

Alternative Name: RPA3 (RPA3 Products)

Synonyms: REPA3 antibody, 14kDa antibody, C330026P08Rik antibody, im:6908405 antibody, zgc:56310 antibody, zgc:86697 antibody, rpa3 antibody, MGC82610 antibody, RPA3 antibody, repa3 antibody, replication protein A3 antibody, replication protein A3 S homeolog antibody, replication protein A3 L homeolog antibody, RPA3 antibody, Rpa3 antibody, rpa3 antibody, rpa3.S antibody, rpa3.L antibody

Background:

Background: Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Ref.7 Ref.9 Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair, it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.

Aliases: p14 antibody, REPA 3 antibody, REPA3 antibody, Replication factor A protein 3 antibody, Replication protein A 14 kDa subunit antibody, Replication protein A3 14kD antibody, Replication protein A3 14 kDa antibody, Replication protein A3 antibody, RF A antibody, RF A protein 3 antibody, RF-A protein 3 antibody, RFA protein 3 antibody, RFA3_HUMAN antibody, RP A antibody, RP A p14 antibody, RP-A p14 antibody, RPA 14 antibody, RPA 3 antibody, RPA p14 antibody, rpa3 antibody

UniProt: P35244

Pathways: Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA