CARM1 antibody (N-Term)
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- Target See all CARM1 Antibodies
- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CARM1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- Rabbit polyclonal CARM1 antibody was raised against a 19 amino acid peptide near the amino terminus of human CARM1.
- Isotype
- IgG
- Top Product
- Discover our top product CARM1 Primary Antibody
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- Application Notes
- CARM1 antibody can be used for detection of CARM1 by Western blot at 1 - 2 μg/mL.
- Comment
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(NT) Coactivator-associated arginine methyltransferase 1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Storage
- 4 °C
- Storage Comment
- CARM1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Expiry Date
- 12 months
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- Target
- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
- Alternative Name
- CARM1 (CARM1 Products)
- Synonyms
- NV18905 antibody, prmt4 antibody, PRMT4 antibody, Prmt4 antibody, si:dkey-204f11.63 antibody, zgc:100805 antibody, coactivator associated arginine methyltransferase 1 antibody, coactivator associated arginine methyltransferase 1 L homeolog antibody, coactivator-associated arginine methyltransferase 1 antibody, histone-arginine methyltransferase CARM1 antibody, CARM1 antibody, carm1.L antibody, Carm1 antibody, carm1 antibody, LOC100352221 antibody
- Background
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Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation. CARM1 functions as a transcriptional co-activator for various nuclear receptors and NF-kB. It has also been shown to methylate histone H3 arginines, inhibiting the binding of corepressors and protecting chromatin from deacetylation, thereby facilitating transcription.
Synonyms: Coactivator-associated arginine methyltransferase 1, PRMT4 - Molecular Weight
- 67 kDa (calculated)
- Gene ID
- 10498
- NCBI Accession
- NP_954592
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation
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