SDPR antibody (N-Term)
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- Target See all SDPR Antibodies
- SDPR (Serum Deprivation Response (SDPR))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SDPR antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- It is predicted to not cross-react with other members of the cavin family.
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- Rabbit polyclonal SDPR antibody was raised against an 18 amino acid peptide near the amino terminus of human SDPR.
- Isotype
- IgG
- Top Product
- Discover our top product SDPR Primary Antibody
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- Application Notes
- SDPR antibody can be used for detection of SDPR by Western blot at 1 - 2 μg/mL.
- Comment
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(NT) Serum deprivation-response protein
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Storage
- 4 °C/-20 °C
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- Target
- SDPR (Serum Deprivation Response (SDPR))
- Alternative Name
- SDPR (SDPR Products)
- Synonyms
- CAVIN2 antibody, PS-p68 antibody, SDR antibody, cavin-2 antibody, sdr antibody, MGC84112 antibody, sdprb antibody, wu:fb39c08 antibody, wu:fk90b02 antibody, zgc:92231 antibody, caveolae associated protein 2 antibody, caveolae associated 2 antibody, caveolae associated protein 2 S homeolog antibody, serum deprivation response antibody, caveolae associated protein 2b antibody, CAVIN2 antibody, Cavin2 antibody, cavin2.S antibody, SDPR antibody, cavin2b antibody
- Background
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The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.
Synonyms: Serum deprivation response, SDR, serum deprivation-response protein, CAVIN2, PS-p68, cavin-2, phosphatidylserine binding protein - Molecular Weight
- 47 kDa
- Gene ID
- 8436
- NCBI Accession
- NP_004648
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