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HAX1 Protein (His tag)

HAX1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % by SDS - PAGE SDS
Catalog No. ABIN1098543
  • Target See all HAX1 Proteins
    HAX1 (HCLS1 Associated Protein X-1 (HAX1))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This HAX1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 80 % by SDS - PAGE
    Top Product
    Discover our top product HAX1 Protein
  • Comment

    Synonyms: HCLS1 associated protein X-1 isoform a, HCLSBP1, HS1BP1, SCN3

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1 M NaCl
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    HAX1 (HCLS1 Associated Protein X-1 (HAX1))
    Alternative Name
    HAX1 (HAX1 Products)
    Synonyms
    HAX1 Protein, hax1 Protein, HCLSBP1 Protein, HS1BP1 Protein, SCN3 Protein, HAX-1 Protein, Hs1bp1 Protein, HSP1BP-1 Protein, SIG-111 Protein, Silg111 Protein, mHAX-1s Protein, HCLS1 associated protein X-1 Protein, HCLS1 associated X-1 Protein, HAX1 Protein, hax1 Protein, Hax1 Protein
    Background
    HAX1 is known to associate with HS1, a substrate of Src family tyrosine kinases. It also interacts with the product of PKD2, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with F-actin-binding protein, cortactin. It is associated with autosomal recessive severe congenital neutropenia, also known as Kostmann syndrome. Recombinant human HAX1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    33.7 kDa(299aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_006109
    Pathways
    Regulation of Actin Filament Polymerization
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