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HAX1 Products

(HCLS1 Associated Protein X-1 (HAX1))
The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured HAX1 Categories

HAX1 Antibodies

High quality antibodies with extensive validation data.

HAX1 ELISA Kits

Reliable ELISA kits for a wide range of species.

HAX1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HAX1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (5)
Cat. No. ABIN2855251
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7154840
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7261502
Quantity 200 μL
Datasheet Datasheet

Recommended HAX1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1136117
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1136116
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1136118
Quantity 96 tests
Datasheet Datasheet

Recommended HAX1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306379
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306381
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN1098543
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our HAX1 products

Gomathinayagam, Muralidharan, Ha, Varadarajalu, Dhanasekaran: "Hax-1 is required for Rac1-Cortactin interaction and ovarian carcinoma cell migration." in: Genes & cancer, Vol. 5, Issue 3-4, pp. 84-99, (2014) (PubMed).

Chao, Parganas, Boyd, Hong, Opferman, Ihle: "Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons." in: Nature, Vol. 452, Issue 7183, pp. 98-102, (2008) (PubMed).

Suzuki, Demoliere, Kitamura, Takeshita, Deuschle, Watanabe: "HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 6, pp. 2736-44, (1997) (PubMed).

Synonyms and alternative names related to HAX1

HCLS1 associated protein X-1 (HAX1), HCLS1 associated protein X-1 (hax1), HCLS1 associated protein X-1 (Hax1), HCLS1 associated X-1 (Hax1), HAX-1, HAX1, hax1, HCLSBP1, HS1BP1, Hs1bp1, HSP1BP-1, mHAX-1s, SCN3, SIG-111, Silg111

Protein level used designations for HAX1

  • HCLS1 associated protein X-1
  • HCLS1-associated protein X-1
  • HAX-1
  • HCLS1 (and PKD2) associated protein
  • HS1 binding protein
  • HS1-associating protein X-1
  • HS1-binding protein 1
  • HSP1BP-1
  • HS1-associated protein X-1
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