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ABI1 antibody (C-Term)
ABI1
Reactivity: Human, Rat, Mouse
WB, IHC (p), IF, IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ABI1 Antibody
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Target
See all ABI1 Antibodies
ABI1
(Abl-Interactor 1 (ABI1))
Binding Specificity
All epitopes for ABI1 antibodies
C-Term
Reactivity
All reactivities for ABI1 antibodies
Human, Rat, Mouse
Host
All hosts for ABI1 antibodies
Rabbit
Clonality
All clonalities for ABI1 antibodies
Polyclonal
Conjugate
All conjugates for ABI1 antibodies
This ABI1 antibody is un-conjugated
Application
All applications for ABI1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
Specificity
This antibody detects ABI1 / SSH3BP1 (C-term).
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Immunogen affinity purified
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminal of human ABI-1 .Remarks: Sequence is different from the related rat and mouse sequence by single amino acid
Isotype
IgG
Top Product
Discover our top product ABI1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Reconstitution
0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer
5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
Preservative
Sodium azide, Thimerosal (Merthiolate)
Precaution of Use
This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target Details for ABI1
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Target
ABI1
(Abl-Interactor 1 (ABI1))
Alternative Name
ABI1 / SSH3BP1 (ABI1 Products )
Synonyms
ABI-1 antibody, ABLBP4 antibody, E3B1 antibody, NAP1BP antibody, SSH3BP antibody, SSH3BP1 antibody, NAP1 antibody, Ssh3bp1 antibody, E3b1 antibody, abi1 antibody, wu:fc66g09 antibody, wu:fk56a10 antibody, zgc:73174 antibody, MGC84356 antibody, ABI1 antibody, abi-1 antibody, e3b1 antibody, nap1bp antibody, ssh3bp antibody, ssh3bp1 antibody, wu:fe48a10 antibody, zgc:153534 antibody, DKFZp469P1319 antibody, abl interactor 1 antibody, abl-interactor 1 antibody, abl-interactor 1a antibody, abl interactor 1 S homeolog antibody, abl-interactor 1b antibody, Abl-interactor 1 antibody, Abl interactor 1 antibody, ABI1 antibody, Abi1 antibody, abi1a antibody, abi1.S antibody, abi1 antibody, abi1b antibody, Bm1_44660 antibody, LOAG_04356 antibody
Background
ABI1 is a human homolog of mouse Abl-interactor-1 (Abi1), mapped on 10p11.2. ABI1 participate in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor (GEF) activities. ABI1 dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA,but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins.ABI1 plays a role in the leukemogenesis by translocating to MLL.Synonyms: Abelson interactor 1, Abi-1, Abl interactor 1, Abl-binding protein 4, AblBP4, Eps8 SH3 domain-binding protein, Nap1-binding protein, Spectrin SH3 domain-binding protein 1, Spectrin binding protein, e3B1
Gene ID
10006
NCBI Accession
NP_001012768
UniProt
Q8IZP0
Pathways
RTK Signaling , Response to Water Deprivation , ER-Nucleus Signaling
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