alpha Fetoprotein antibody (alpha-Fetoprotein)

Details for Product anti-AFP Antibody No. ABIN1105327, Supplier: Log in to see
Antigen
  • FETA
  • HPAFP
  • alpha-fetoprotein
  • alpha fetoprotein
  • AFP
  • Afp
Alternatives
anti-Human alpha Fetoprotein antibody for ELISA
Reactivity
Human
1060
114
64
64
56
31
10
10
7
4
3
3
1
Host
Mouse
751
306
47
9
6
2
Clonality (Clone)
Monoclonal ()
Conjugate
This alpha Fetoprotein antibody is un-conjugated
60
51
44
29
19
18
16
16
16
14
13
12
12
12
12
12
12
11
11
9
7
5
5
3
3
3
3
3
2
2
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
520
437
265
222
204
146
101
66
59
44
35
29
14
12
10
8
7
6
4
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Human Alpha-Fetoprotein
Clone AP-1
Isotype IgG2b
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity Chromatography.
Background Alpha-fetoprotein (AFP) is a major plasma protein in the fetus, where it is produced by the yolk sac and liver. Direct confirmation of the assignment of the AFP gene to chromosome 4 by in situ hybridization was provided by Harper and Dugaiczyk (1983), who placed the gene in the q11-q22 region, the same region as the albumin gene. Structure and evolution of human alpha-fetoprotein deduced from partial sequence of cloned cDNA.As the major fetal serum protein, Alpha-fetoprotein is not essential for embryonic development but is required for female fertility.Synonyms: Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP
Gene ID 174
NCBI Accession NP_001125
UniProt P02771
Research Area Serum/Plasma Proteins
Pathways C21-Steroid Hormone Metabolic Process
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Reconstitution Restore with 1.2 % Sodium Acetate or neutral PBS
Concentration 0.1 mg/mL
Buffer 1.2 % Sodium Acetate containing 2 mg BSA and 0.01 mg Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (IHC) image for anti-alpha-Fetoprotein (AFP) antibody (ABIN1105327) anti-alpha-Fetoprotein (AFP) antibody
Background publications Gabant, Forrester, Nichols, Van Reeth, De Mees, Pajack, Watt, Smitz, Alexandre, Szpirer, Szpirer: "Alpha-fetoprotein, the major fetal serum protein, is not essential for embryonic development but is required for female fertility." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 20, pp. 12865-70, 2002 (PubMed).

Beattie, Dugaiczyk: "Structure and evolution of human alpha-fetoprotein deduced from partial sequence of cloned cDNA." in: Gene, Vol. 20, Issue 3, pp. 415-22, 1983 (PubMed).

DEustachio, Ingram, Tilghman, Ruddle: "Murine alpha-fetoprotein and albumin: two evolutionarily linked proteins encoded on the same mouse chromosome." in: Somatic cell genetics, Vol. 7, Issue 3, pp. 289-94, 1981 (PubMed).

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