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C1S antibody (activated)

C1S Reactivity: Human WB, IHC (p), IP, IHC (fro), EIA, Func Host: Mouse Monoclonal M241 unconjugated

Catalog No. ABIN1105613

Datasheet as PDF

Target See all C1S Antibodies

C1S (Complement Component 1, S Subcomponent (C1S))
Binding Specificity
15

5

3

3

2

1

1

1

1

1

1

1
activated
Reactivity
55

18

18

2

1
Human
Host
43

10

2
Mouse
Compatible Secondaries
Clonality
46

9
Monoclonal
Conjugate
32

4

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This C1S antibody is un-conjugated
Application
39

17

15

13

13

11

9

7

7

7

6

3

2

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Functional Studies (Func)

Cross-Reactivity (Details)

Species reactivity (tested):Human

Purification

Protein G

Clone

M241

Isotype

IgG2a

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anti-Complement Component 1, S Subcomponent (C1S) (AA 1-688) antibody
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anti-Complement Component 1, S Subcomponent (C1S) (C-Term) antibody
C1S Reactivity: Human WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Complement Component 1, S Subcomponent (C1S) antibody
C1S Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Complement Component 1, S Subcomponent (C1S) antibody
C1S Reactivity: Human, Rat IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Complement Component 1, S Subcomponent (C1S) antibody
C1S Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated

anti-Complement Component 1, S Subcomponent (C1S) antibody
C1S Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated

anti-Complement Component 1, S Subcomponent (C1S) (AA 1-688) antibody
C1S Reactivity: Human WB Host: Mouse Polyclonal unconjugated

anti-Complement Component 1, S Subcomponent (C1S) antibody
C1S Reactivity: Human WB, FACS Host: Mouse Monoclonal 2F5 unconjugated

anti-Complement Component 1, S Subcomponent (C1S) antibody
C1S Reactivity: Human IHC, ELISA, IHC (p) Host: Goat Polyclonal unconjugated

anti-Complement Component 1, S Subcomponent (C1S) (AA 438-685) antibody
C1S Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Concentration

0.1 mg/mL

Buffer

PBS, 0.1 % bovine serum albumin

Storage

4 °C

Storage Comment

Store at 2 - 8 °C.
Target

C1S (Complement Component 1, S Subcomponent (C1S))

Alternative Name

C1s (C1S Products)

Synonyms

AA959438 antibody, AI255193 antibody, AI327365 antibody, C1sa antibody, r-gsp antibody, C1S antibody, complement C1s antibody, complement component 1, s subcomponent 1 antibody, complement component 1, s subcomponent antibody, complement component 1, s subcomponent L homeolog antibody, complement C1s subcomponent antibody, C1S antibody, C1s1 antibody, C1s antibody, c1s antibody, c1s.L antibody, LOC100558615 antibody

Background

C protein activated C1s is a subcomponent of the first component of C (C1). Activated C1s is a glycosylated single-polypeptide zymogen of 85 kD. Activation of the proenzyme C1s occurs through cleavage by the active form of C1r. The activated protease, activated C1s, consists of a disulfide-linked H chain and a L chain. Activated C1s is a serine protease and its catalytic site is located in the L chain. Activation of the classical C pathway is triggered by activated C1s which cleaves C4 and C2 to form the C3 convertase, C4bC2a.Synonyms: C1 esterase, Complement 1s, Complement C1s, Complement C1s subcomponent, Complement component 1 subcomponent s

Gene ID

9606

UniProt

P09871

Pathways

Complement System