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C1S antibody (activated)
C1S
Reactivity: Human
WB, IHC (p), IP, IHC (fro), EIA, Func
Host: Mouse
Monoclonal
M241
unconjugated
Product Details anti-C1S Antibody
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Target
See all C1S Antibodies
C1S
(Complement Component 1, S Subcomponent (C1S))
Binding Specificity
All epitopes for C1S antibodies
activated
Reactivity
All reactivities for C1S antibodies
Human
Host
All hosts for C1S antibodies
Mouse
Clonality
All clonalities for C1S antibodies
Monoclonal
Conjugate
All conjugates for C1S antibodies
This C1S antibody is un-conjugated
Application
All applications for C1S antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Functional Studies (Func)
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Protein G
Clone
M241
Isotype
IgG2a
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.1 mg/mL
Buffer
PBS, 0.1 % bovine serum albumin
Storage
4 °C
Storage Comment
Store at 2 - 8 °C.
Target Details for C1S
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Target
C1S
(Complement Component 1, S Subcomponent (C1S))
Alternative Name
C1s (C1S Products )
Synonyms
AA959438 antibody, AI255193 antibody, AI327365 antibody, C1sa antibody, r-gsp antibody, C1S antibody, complement C1s antibody, complement component 1, s subcomponent 1 antibody, complement component 1, s subcomponent antibody, complement component 1, s subcomponent L homeolog antibody, complement C1s subcomponent antibody, C1S antibody, C1s1 antibody, C1s antibody, c1s antibody, c1s.L antibody, LOC100558615 antibody
Background
C protein activated C1s is a subcomponent of the first component of C (C1). Activated C1s is a glycosylated single-polypeptide zymogen of 85 kD. Activation of the proenzyme C1s occurs through cleavage by the active form of C1r. The activated protease, activated C1s, consists of a disulfide-linked H chain and a L chain. Activated C1s is a serine protease and its catalytic site is located in the L chain. Activation of the classical C pathway is triggered by activated C1s which cleaves C4 and C2 to form the C3 convertase, C4bC2a.Synonyms: C1 esterase, Complement 1s, Complement C1s, Complement C1s subcomponent, Complement component 1 subcomponent s
Gene ID
9606
UniProt
P09871
Pathways
Complement System
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