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MME antibody

MME Reactivity: Human IHC (p) Host: Mouse Monoclonal 2A1H5E1 unconjugated
Catalog No. ABIN1105719
  • Target See all MME Antibodies
    MME (Membrane Metallo-Endopeptidase (MME))
    Reactivity
    • 207
    • 58
    • 50
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 111
    • 102
    • 2
    Mouse
    Clonality
    • 109
    • 105
    • 2
    Monoclonal
    Conjugate
    • 108
    • 19
    • 18
    • 13
    • 9
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MME antibody is un-conjugated
    Application
    • 132
    • 97
    • 78
    • 67
    • 35
    • 28
    • 22
    • 20
    • 13
    • 13
    • 10
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    Recognizes CD10
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Purified
    Clone
    2A1H5E1
    Isotype
    IgG2b
    Top Product
    Discover our top product MME Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS, 0.03 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    MME (Membrane Metallo-Endopeptidase (MME))
    Alternative Name
    CD10 / Neprilysin (MME Products)
    Synonyms
    CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody
    Target Type
    Chemical
    Background
    CD10 is a 100 kDa glycoprotein, also designated Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.Synonyms: Atriopeptidase, CALLA, Common acute lymphocytic leukemia antigen, EPN, Enkephalinase, MME, NEP, Neutral endopeptidase, Neutral endopeptidase 24.11
    Gene ID
    4311
    Pathways
    RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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