MEK1 antibody

Catalog No. ABIN110583

The Rabbit Polyclonal anti-MEK1 antibody (ABIN110583) specifically detects MEK1 in WB. The antibody is reactive with Human samples.

Quick Overview for MEK1 antibody (ABIN110583)

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEK1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MEK1 Antibody

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Storage: 4 °C

Target Details for MEK1

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Alternative Name: Mek1 (MAP Kinase Kinase)

Background: MEK1 is one of the MEKs that are upstream of the MAPK ERK1/2. MEK1 is a dual-specific protein kinase that phosphorylates ERK1/2 on boththreonine and tyrosine residues in the sequence TEY. Phosphorylation of these residues dramatically activates ERK1/2, which then phosphorylate their downstream substrate. MEK1 contains 393 amino acids and has a calculated molecular weight of 43,470. MEK1 itself is regulated by phos-phorylation by one of the MEK kinases.

Pathways: MAPK Signaling, RTK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling