CDKN2D antibody

Catalog No. ABIN1106659

This Mouse Monoclonal antibody specifically detects CDKN2D in WB, IP, IHC (p) and IF. It exhibits reactivity toward Human.

Quick Overview for CDKN2D antibody (ABIN1106659)

Target: CDKN2D (Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDKN2D antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Clone: IMD-19

Product Details anti-CDKN2D Antibody

Specificity: This antibody recognizes Human p19INK4d and shows no cross reactivity with other proteins.

Purification: Affinity chromatography

Immunogen: Recombinant human p19INK4d.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1.2 % Sodium Acetate or neutral PBS

Concentration: 0,1 mg/mL

Buffer: 1.2 % Sodium Acetate, 0.01 mg Sodium Azide, 2 mg BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CDKN2D

Target: CDKN2D (Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D))

Alternative Name: CDKN2D / p19INK4d

Background: Cyclins are important in regulating the cell cycle through their formation of enzymatic complexes with various cyclin-dependent kinases. P19(INK4d) also kowns as cyclin-dependent kinase inhibitor 2D, is one of the novel members of the mouse INK4 gene family. Okuda et al. (1995) described the cloning of the human INK4d gene (CDKN2D). The predicted 166-amino acid protein is 86 % identical to the mouse protein and about 45 % identical to other human INK4 family members.Synonyms: Cyclin-dependent kinase 4 inhibitor D, INK4D, p19, p19-INK4d

Gene ID: 1032

NCBI Accession: NP_001791

UniProt: P55273

Pathways: Cell Division Cycle, Sensory Perception of Sound, Mitotic G1-G1/S Phases, Negative Regulation of intrinsic apoptotic Signaling