C-EHKSLESLAD GGS Remarks: Percent identity with other species by BLAST analysis: Human (100%), Gibbon (92%), Monkey (92%), Marmoset (85%), Bovine (85%), Rabbit (85%).
Specificity
This antibody detects FANCE.
Cross-Reactivity (Details)
Species reactivity (expected):BovineSpecies reactivity (tested):Human.
Purification
Immunoaffinity Chromatography
Immunogen
Synthetic peptide from an internal region of Human FANCE (NP_068741.1).
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Background
FANCE promotes the nuclear accumulation of FANCC. FANCE protein is part of the FA nuclear complex, binding FANCC & FANCD2. It is required for the nuclear accumulation of FANCC and provides a bridge between the FA complex and FANCD2. FANCC mutants do not bind FANCE or prevent chromosome breakage.Synonyms: FACE, Fanconi anemia group E protein