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IFNG antibody (Interferon gamma)

Details for Product anti-IFNG Antibody No. ABIN1107642, Supplier: Log in to see
Antigen
  • IFNG2
  • IFN-g
  • Ifg
  • IFN-G
  • IFN-gamma
  • IFNG
  • IFG
  • IFI
  • interferon gamma
  • interferon gamma-like
  • interferon, gamma
  • Ifng
  • IFNG
  • LOC101337436
Alternatives
anti-Human IFNG antibody for Enzyme Immunoassay
Reactivity
Human
754
272
148
68
37
37
37
32
31
26
24
22
22
18
18
13
13
11
10
10
10
10
9
6
6
5
2
2
1
1
Host
Mouse
699
395
182
30
8
7
4
3
1
Clonality (Clone)
Monoclonal ()
Conjugate
This IFNG antibody is un-conjugated
160
120
73
54
34
21
20
16
14
12
12
11
10
8
8
8
8
7
7
6
6
6
6
6
4
4
4
4
3
3
3
3
3
3
2
2
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
738
692
469
168
132
127
67
67
66
65
49
38
37
25
24
20
14
13
11
9
7
6
5
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Options
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Immunogen Ni-NTA purified recombinant human IFN-gamma expressed in E. Coli strain BL21 (DE3)
Clone 3F1E3
Isotype IgG1
Specificity This antibody recognizes Recombinant IFNG / Interferon gamma Western Blot and ELISA. Other species not tested.
Purification Affinity Chromatography on Protein A
Alternative Name IFNG / Interferon gamma (IFNG Antibody Abstract)
Background Interferon-γ (IFN-γ) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-γ strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB.Synonyms: IFN-gamma, gamma IFN
Gene ID 3458
NCBI Accession NP_000610
UniProt P01579
Pathways Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-IFNG antibody (Interferon gamma) (ABIN1107642) anti-Interferon gamma (IFNG) antibody
Background publications Takayanagi, Ogasawara, Hida, Chiba, Murata, Sato, Takaoka, Yokochi, Oda, Tanaka, Nakamura, Taniguchi: "T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma." in: Nature, Vol. 408, Issue 6812, pp. 600-5, 2000 (PubMed).

Tsubota, Fukagawa, Fujihara, Shimmura, Saito, Saito, Takeuchi: "Regulation of human leukocyte antigen expression in human conjunctival epithelium." in: Investigative ophthalmology & visual science, Vol. 40, Issue 1, pp. 28-34, 1999 (PubMed).