IFNG antibody (Interferon gamma)

Details for Product anti-IFNG Antibody No. ABIN1107646, Supplier: Log in to see
Antigen
  • IFNG2
  • IFN-g
  • Ifg
  • IFN-G
  • IFN-gamma
  • IFNG
  • IFG
  • IFI
  • interferon gamma
  • interferon gamma-like
  • interferon, gamma
  • Ifng
  • IFNG
  • LOC101337436
Alternatives
anti-Human IFNG antibody for Blocking Antibody
Reactivity
Human
775
278
144
71
47
42
32
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31
24
23
22
22
18
17
13
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13
10
10
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10
9
6
5
4
2
1
1
1
Host
Mouse
714
394
193
31
8
6
5
4
3
1
Clonality (Clone)
Monoclonal ()
Conjugate
This IFNG antibody is un-conjugated
155
115
73
50
37
26
26
20
17
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15
11
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11
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10
9
9
9
9
8
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4
4
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3
3
3
3
3
2
2
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
709
655
516
183
133
125
92
86
85
65
49
44
38
31
23
20
13
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11
9
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4
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2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Options
Supplier
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Available images

Clone 3F1E3
Isotype IgG1
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Purified
Alternative Name IFNG / Interferon gamma (IFNG Antibody Abstract)
Background Interferon-γ (IFN-γ) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-γ strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKBSynonyms: IFN-gamma, gamma IFN
Gene ID 3458
Pathways Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer PBS, 0.03 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-IFNG antibody (Interferon gamma) (ABIN1107646) anti-Interferon gamma (IFNG) antibody
Background publications Takayanagi, Ogasawara, Hida, Chiba, Murata, Sato, Takaoka, Yokochi, Oda, Tanaka, Nakamura, Taniguchi: "T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma." in: Nature, Vol. 408, Issue 6812, pp. 600-5, 2000 (PubMed).

Tsubota, Fukagawa, Fujihara, Shimmura, Saito, Saito, Takeuchi: "Regulation of human leukocyte antigen expression in human conjunctival epithelium." in: Investigative ophthalmology & visual science, Vol. 40, Issue 1, pp. 28-34, 1999 (PubMed).