You are viewing an incomplete version of our website. Please click to reload the website as full version.

Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (C-Term) antibody

Details for Product No. ABIN1108490, Supplier: Log in to see
Antigen
  • AA209988
  • AI551208
  • CAR
  • CAR-beta
  • CAR1
  • Care2
  • CXR
  • ESTM32
  • MB67
Alternatives
anti-Mouse (Murine) Nuclear Receptor Subfamily 1, Group I, Member 3 antibody for Immunohistochemistry
Epitope
C-Term
17
15
15
14
11
6
5
3
3
2
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
104
22
13
4
3
2
1
1
1
Host
Rabbit
91
20
Clonality
Polyclonal
Conjugate
Un-conjugated
6
5
5
2
2
2
Application
Western Blotting (WB)
97
50
26
12
5
3
2
1
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen The immunogen for anti-NR1I3 antibody: synthetic peptide directed towards the C terminal of human NR1I3.
Sequence FHGTLRKLQL QEPEYVLLAA MALFSPDRPG VTQRDEIDQL QEEMALTLQS
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat, Pig, DogSpecies reactivity (tested):Human
Purification Purified using Protein A affinity column
Alternative Name NR1I3 / CAR (NR1I3 Antibody Abstract)
Background NR1I3 is a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members.Synonyms: Constitutive activator of retinoid response, Constitutive androstane receptor, MB67, Nuclear receptor subfamily 1, Orphan nuclear receptor MB67, group I, member 3
Gene ID 9970
NCBI Accession NP_005113
Pathways Nuclear Receptor Transcription Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Reconstitution Add 100 μL of distilled water to a final concentration of 1 mg/mL.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
Supplier Images
Western Blotting (WB) image for anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (C-Term) antibody (ABIN1108490) Human HepG2; WB Suggested Anti-NR1I3 Antibody Titration: 1.25ug/ml. Positive Control:...
Background publications Ferguson, Chen, LeCluyse, Negishi, Goldstein: "Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha." in: Molecular pharmacology, Vol. 68, Issue 3, pp. 747-57, 2005