PCYOX1 antibody (C-Term)

Catalog No. ABIN1108602

Product Details anti-PCYOX1 Antibody

Target: PCYOX1 (Prenylcysteine Oxidase 1 (PCYOX1))

Binding Specificity: C-Term

Reactivity: Human, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCYOX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequence: IFSQETLTKA QILKLFLSYD YAVKKPWLAY PHYKPPEKCP SIILHDRLYY

Cross-Reactivity (Details): Species reactivity (expected):Dog, BovineSpecies reactivity (tested):Human

Purification: Purified using Protein A affinity column.

Immunogen: The immunogen for anti-PCYOX1 antibody: synthetic peptide directed towards the C terminal of human PCYOX1.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for PCYOX1

Target: PCYOX1 (Prenylcysteine Oxidase 1 (PCYOX1))

Alternative Name: PCYOX1 (PCYOX1 Products)

Background: Prenylated proteins contain one of two isoprenoid lipids, either the 15-carbon farnesyl or the 20-carbon geranylgeranyl, covalently attached to cysteine residues at or near their C terminus. PCYOX1 is capable of cleaving the thioether bond of prenylcysteines. The enzyme was isolated from bovine brain membranes and exhibits an apparent molecular mass of 63 kDa. This is a specific enzyme involved in prenylcysteine metabolism in mammalian cells, most likely comprising the final step in the degradation of prenylated proteins.Synonyms: KIAA0908, PCL1, Prenylcysteine lyase, Prenylcysteine oxidase 1

Gene ID: 51449

NCBI Accession: NP_057381