PCYOX1 antibody (C-Term)

Catalog No. ABIN2777705

This Rabbit Polyclonal antibody specifically detects PCYOX1 in WB and IHC. It exhibits reactivity toward Human, Cow, Dog, Horse, Pig, Rabbit and Saccharomyces cerevisiae.

Quick Overview for PCYOX1 antibody (C-Term) (ABIN2777705)

Target: PCYOX1 (Prenylcysteine Oxidase 1 (PCYOX1))

Reactivity: Human, Cow, Dog, Horse, Pig, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCYOX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PCYOX1 Antibody

Binding Specificity: C-Term

Purpose: PCYOX1 Antibody - C-terminal region

Sequence: IFSQETLTKA QILKLFLSYD YAVKKPWLAY PHYKPPEKCP SIILHDRLYY

Predicted Reactivity: Cow: 83%, Dog: 86%, Horse: 86%, Human: 100%, Pig: 83%, Rabbit: 100%, Yeast: 75%

Characteristics: This is a rabbit polyclonal antibody against PCYOX1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PCYOX1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108883

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PCYOX1

Target: PCYOX1 (Prenylcysteine Oxidase 1 (PCYOX1))

Alternative Name: PCYOX1

Background:

Background Information: Prenylated proteins contain one of two isoprenoid lipids, either the 15-carbon farnesyl or the 20-carbon geranylgeranyl, covalently attached to cysteine residues at or near their C terminus. PCYOX1 is capable of cleaving the thioether bond of prenylcysteines. The enzyme was isolated from bovine brain membranes and exhibits an apparent molecular mass of 63 kDa. This is a specific enzyme involved in prenylcysteine metabolism in mammalian cells, most likely comprising the final step in the degradation of prenylated proteins.

Gene Name: Prenylcysteine oxidase 1

Alternative Symbols: PCL1

Protein Name: Prenylcysteine oxidase 1

Molecular Weight: 57kDa

Gene ID: 51449

NCBI Accession: NP_057381

UniProt: Q9UHG3