PIWIL1 antibody (Internal Region)
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- Target See all PIWIL1 Antibodies
- PIWIL1 (Piwi-Like 1 (PIWIL1))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat, Dog, Pig
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This PIWIL1 antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Sequence
- C-SNRKDKYDAI KKY
- Specificity
- This antibody is expected to recognise both reported isoforms (NP_004755.2, NP_001177900.1).
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse, Rat, Canine (Dog), Porcine.
Species reactivity (tested):Human. - Purification
- Affinity Chromatography
- Immunogen
- Synthetic peptide (C-SNRKDKYDAIKKY) from the internal region of the protein sequence according to NP_004755.2, NP_001177900.1. Genename: PIWIL1
- Top Product
- Discover our top product PIWIL1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- PIWIL1 (Piwi-Like 1 (PIWIL1))
- Alternative Name
- PIWIL1 (PIWIL1 Products)
- Synonyms
- ziwi antibody, PIWI antibody, HIWI antibody, MIWI antibody, piwi like RNA-mediated gene silencing 1 antibody, PIWI-like protein 1 antibody, putative PIWI-like protein 1 antibody, putative argonaut-like protein antibody, piwi-like RNA-mediated gene silencing 1 antibody, PIWIL1 antibody, Tb10.70.5520 antibody, LINJ_21_0470 antibody, LBRM_21_0470 antibody, piwil1 antibody, Piwil1 antibody
- Background
- PIWI-L1 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. PIWI-L1 is thought to play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells as removing PIWI-L1 protein from single germline stem cells significantly decreases the rate of their division. Recent studies have shown that overexpression of PIWI-L1 (as well as other PIWI-like proteins) are potential biomarkers for colon and other cancers.Synonyms: HIWI, Piwi-like protein 1
- Gene ID
- 9271
- NCBI Accession
- NP_001177900
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