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S100A9 antibody
S100A9
Reactivity: Human
WB, IHC (p), EIA, IHC (fro)
Host: Mouse
Monoclonal
47-8D3
unconjugated
Product Details anti-S100A9 Antibody
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Target
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S100A9
(S100 Calcium Binding Protein A9 (S100A9))
Reactivity
All reactivities for S100A9 antibodies
Human
Host
All hosts for S100A9 antibodies
Mouse
Clonality
All clonalities for S100A9 antibodies
Monoclonal
Conjugate
All conjugates for S100A9 antibodies
This S100A9 antibody is un-conjugated
Application
All applications for S100A9 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Purified
Immunogen
A BALB/c mouse was immunized with human peripheral blood monocyte components. Splenocytes were fused with Mouse myeloma cell line NS-1.
Clone
47-8D3
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.1 mg/mL
Buffer
PBS, 0.05 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for S100A9
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Target
S100A9
(S100 Calcium Binding Protein A9 (S100A9))
Alternative Name
S100A9 / Calgranulin-B / MRP14 (S100A9 Products )
Synonyms
60B8AG antibody, CAGB antibody, CFAG antibody, CGLB antibody, L1AG antibody, LIAG antibody, MAC387 antibody, MIF antibody, MRP14 antibody, NIF antibody, P14 antibody, Mrp14 antibody, S100A9 antibody, MRP-14 antibody, p14 antibody, 60B8Ag antibody, AW546964 antibody, BEE22 antibody, Cagb antibody, GAGB antibody, L1Ag antibody, S100 calcium binding protein A9 antibody, S100 calcium binding protein A9 (calgranulin B) antibody, S100A9 antibody, S100a9 antibody
Background
S100A9 is a member of the S100 family of proteins. S100A9, together with S100A8 forms a heterodimeric protein complex, Calprotectin, which is a major calcium- and zinc-binding protein in the cytosol of neutrophils, monocytes, and keratinocytes. Complexes of S100A8 and S100A9 are the physiologically relevant forms of these proteins. S100A9 may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. Its expression and potential cytokine-like function in inflammation and in cancer suggest that S100A8/A9 may play a key role in inflammation-associated cancer.Synonyms: CAGB, Calprotectin L1H subunit, Leukocyte L1 complex heavy chain, MRP-14, Migration inhibitory factor-related protein 14, S100 calcium-binding protein A9, S100-A9
Gene ID
9606
UniProt
P06702
Pathways
Transition Metal Ion Homeostasis , Positive Regulation of Endopeptidase Activity , S100 Proteins
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