TLN1 antibody

Catalog No. ABIN1109198

Product Details anti-TLN1 Antibody

Target: TLN1 (Talin 1 (TLN1))

Reactivity: Human, Mouse, Rat, Chicken, Frog

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLN1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to Talin-1 (TLN1).

Purification: Affinity chromatography

Immunogen: Purified chicken gizzard talin

Clone: Tal-33

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1.2 % sodium acetate or neutral PBS

Concentration: 0,1 mg/mL

Buffer: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TLN1

Target: TLN1 (Talin 1 (TLN1))

Alternative Name: Talin-1 (TLN1) (TLN1 Products)

Synonyms: ILWEQ antibody, TLN antibody, Tln antibody, sb:cb854 antibody, wu:fb05c02 antibody, TLN1 antibody, talin-1 antibody, tln antibody, talin 1 antibody, talin 1 L homeolog antibody, Talin 1 antibody, talin-1 antibody, TLN1 antibody, Tln1 antibody, tln1 antibody, tln1.L antibody, Bm1_56490 antibody, LOC100380665 antibody

Background: Talin is a high-molecular-weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. Talin serves a function of linking vinculin to the integrins, and,thus, the cytoskeleton to extracellular matrix (ECM) receptors. It has a mass of 270 kD and shares 23 % N-terminal identity with ezrin, which has similar functions. TLN gene is mapped to 9p.Synonyms: KIAA1027, TLN

Gene ID: 7094

NCBI Accession: NP_006280

UniProt: Q9Y490

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location