TRIM68 antibody (Middle Region)

Catalog No. ABIN1109337

Product Details anti-TRIM68 Antibody

Target: TRIM68 (Tripartite Motif Containing 68 (TRIM68))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM68 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequence: EPISLELKTD CRVLGLREIL KTYAADVRLD PDTAYSRLIV SEDRKRVHYG

Cross-Reactivity (Details): Species reactivity (expected):Dog, Mouse, Rat, BovineSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogen: The immunogen for anti-TRIM68 antibody: synthetic peptide directed towards the middle region of human TRIM68

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for TRIM68

Target: TRIM68 (Tripartite Motif Containing 68 (TRIM68))

Alternative Name: TRIM68 / RNF137 (TRIM68 Products)

Synonyms: GC109 antibody, RNF137 antibody, SS-56 antibody, SS56 antibody, AI894158 antibody, F730114J12Rik antibody, Rnf137 antibody, TRIM68 antibody, tripartite motif containing 68 antibody, tripartite motif-containing 68 antibody, E3 ubiquitin-protein ligase TRIM68 antibody, TRIM68 antibody, Trim68 antibody, LOC100053519 antibody

Background: The protein encoded by the TRIM68 gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. TRIM68 is expressed in many cancer cell lines. Its expression in normal tissues, however, was found to be restricted to prostate. This gene was also found to be differentially expressed in androgen-dependent versus androgen-independent prostate cancer cells.Synonyms: E3 ubiquitin-protein ligase TRIM68, RING finger protein 137, SS-56, SS56, SSA protein SS-56, Tripartite motif-containing protein 68

Gene ID: 55128

NCBI Accession: NP_060543

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling