TRIM68 antibody (Middle Region)

Catalog No. ABIN2775806

The Rabbit Polyclonal anti-TRIM68 antibody is suitable to detect TRIM68 in samples from Human, Mouse, Rat, Cow, Horse, Pig, Dog, Rabbit, Guinea Pig and Zebrafish (Danio rerio). It has been validated for WB and IHC.

Quick Overview for TRIM68 antibody (Middle Region) (ABIN2775806)

Target: TRIM68 (Tripartite Motif Containing 68 (TRIM68))

Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Dog, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM68 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TRIM68 Antibody

Binding Specificity: Middle Region

Purpose: TRIM68 Antibody - middle region

Sequence: EPISLELKTD CRVLGLREIL KTYAADVRLD PDTAYSRLIV SEDRKRVHYG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 77%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 77%, Rat: 86%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against TRIM68. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIM68

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114745

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM68

Target: TRIM68 (Tripartite Motif Containing 68 (TRIM68))

Alternative Name: TRIM68

Background:

Background Information: The protein encoded by the TRIM68 gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. TRIM68 is expressed in many cancer cell lines. Its expression in normal tissues, however, was found to be restricted to prostate. This gene was also found to be differentially expressed in androgen-dependent versus androgen-independent prostate cancer cells.

Gene Name: Tripartite motif containing 68

Alternative Symbols: SS56, GC109, SS-56, RNF137

Protein Name: E3 ubiquitin-protein ligase TRIM68

Molecular Weight: 56kDa

Gene ID: 55128

NCBI Accession: NP_060543

UniProt: Q96PF7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling