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Antibodies
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anti-Kallikrein-Related Peptidase 3 (KLK3) antibody
Kallikrein-Related Peptidase 3 (KLK3) antibody
| Antigen |
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| Synonyms |
APS, PSA, hK3, KLK2A1, KLK3, KLKB1 |
| Clonality |
Monoclonal (214) |
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Host
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Reactivity
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Application
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ELISA (36), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (34), Western Blotting (WB) (27), Enzyme Immunoassay (EIA) (24), Immunohistochemistry (Frozen Sections) (IHC (fro)) (11), Immunohistochemistry (IHC) (8), Immunoprecipitation (IP) (7), ELISA (Capture) (2), Flow Cytometry (FACS) (2), Immunofluorescence (IF) (2), Radioimmunoassay (RIA) (2), Cell-ELISA (cELISA) (1), ELISA (Detection) (1), Immunoassay (IA) (1), Immunocytochemistry (ICC) (1), Immunoradiometric Assay (IRMA) (1), Lateral Flow (LF) (1)
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| Catalog no. |
ABIN112463 |
| Quantity |
1 mg (1.0 mg/ml) |
| Price |
320.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: Prostate-specific antigen, Semenogelase, Gamma-seminoprotein, P-30 antigen
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Alternative name
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Kallikrein-3 / PSA / KLK3
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Swiss-Prot
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P07288
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Immunogen
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Highly pure PSA from human prostate.
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Isotype
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IgG1 (Matching secondary antibodies)
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Clone
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214
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Description
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Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis andsome have potential as novel cancer and other disease biomarkers. This gene is one of thefifteen kallikrein subfamily members located in a cluster on chromosome 19. Its proteinproduct is a protease present in seminal plasma. It is thought to function normally in theliquefaction of seminal coagulum, presumably by hydrolysis of the high molecular massseminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, isuseful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of thisgene generates two transcript variants encoding different isoforms. Additional transcriptvariants have been described, but it is unclear if these transcripts are normally expressedor if they are specific to benign or malignant tumors.
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Specificity
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This antibody is specific for prostate specific antigen, recognising both the free andcomplexed forms. This antibody can be used as a coating antibody in a two site assay withcatalogue number BM696 as the detection reagent. Species: Human. Others not tested.
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Application Notes
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ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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1.0 mg/ml
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Buffer
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PBS, pH 7.0 containing 0.09% Sodium Azide
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Research Area
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Cell/Tissue Markers, Cancer
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Restrictions
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For Research Use only
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Alternatives for antigen "Kallikrein-Related Peptidase 3 (KLK3)", type "Antibodies"
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Hosts
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Mouse (70), Rabbit (21), Goat (4), Sheep (2), Chicken (1)
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Reactivities
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Human (70)
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Applications
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ELISA (36), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (34), Western Blotting (WB) (27), Enzyme Immunoassay (EIA) (24), Immunohistochemistry (Frozen Sections) (IHC (fro)) (11), Immunohistochemistry (IHC) (8), Immunoprecipitation (IP) (7), ELISA (Capture) (2), Flow Cytometry (FACS) (2), Immunofluorescence (IF) (2), Radioimmunoassay (RIA) (2), Cell-ELISA (cELISA) (1), ELISA (Detection) (1), Immunoassay (IA) (1), Immunocytochemistry (ICC) (1), Immunoradiometric Assay (IRMA) (1), Lateral Flow (LF) (1)
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Conjugates
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Biotin (3), HRP (3)
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Epitopes
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Total (13), C-Term (2)
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Alternatives 
