Prostate Specific Antigen antibody
Quick Overview for Prostate Specific Antigen antibody (ABIN112533)
Target
See all Prostate Specific Antigen (PSA) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- This antibody reacts to PSA.
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Purification
- Affinity chromatography on Protein G- Sepharose
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Immunogen
- Human PSA isolated from pooled human seminal fluid.
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Isotype
- IgG1
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Application Notes
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Western Blot: In Western blotting, a PSA triplet at approximately 30 kDa is observed in theabsence of DTT, and a doublet in the presence of DTT. ELISA: Can be used in a sandwich ELISA with catalogue number BM695 as the coatingantibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.2 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Prostate Specific Antigen (PSA)
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Alternative Name
- Kallikrein-3 / PSA / KLK3
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Background
- Prostate specific antigen (PSA) is a 32 kDa serine kinase produced by the epithelial cells of the prostate. Its function is to liquify the ejaculate and is believed to be involved with dissolving the cervical mucous cap allowing the sperm to enter. Elevated serum levels can be an indication of prostate cancer and are often used as a screening test.Synonyms: Gamma-seminoprotein, P-30 antigen, Prostate-specific antigen, Semenogelase
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Gene ID
- 354
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NCBI Accession
- NP_001025218
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UniProt
- P07288
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Pathways
- Complement System
Target
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