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CD8 antibody

CD8 Reactivity: Mouse FACS, IHC (fro) Host: Rat Monoclonal YTS169-4 unconjugated
Catalog No. ABIN114167
  • Target See all CD8 Antibodies
    CD8
    Reactivity
    • 220
    • 72
    • 26
    • 12
    • 12
    • 11
    • 9
    • 9
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    • 3
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    • 2
    • 2
    Mouse
    Host
    • 224
    • 53
    • 39
    Rat
    Clonality
    • 260
    • 47
    • 2
    Monoclonal
    Conjugate
    • 92
    • 39
    • 31
    • 23
    • 11
    • 8
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
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    • 3
    • 3
    • 3
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    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD8 antibody is un-conjugated
    Application
    • 265
    • 64
    • 63
    • 44
    • 42
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    • 30
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    • 14
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    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This clone recognises the murine CD8 cell surface antigen, expressed by a subset of T lymphocytes.
    Purification
    Affinity chromatography on Protein G
    Clone
    YTS169-4
    Isotype
    IgG2b
    Top Product
    Discover our top product CD8 Primary Antibody
  • Application Notes
    Flow cytometry (1: 50 - 1: 100, use 10 μL to label 10^6 cells in 100 μL. Method sheets areavailable on request). Immunohistochemistry on frozen sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline pH 7.4, containing 0.09 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing. Dilute only prior to immediate use
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CD8
    Alternative Name
    CD8 (CD8 Products)
    Synonyms
    CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody, CD8a molecule antibody, CD8A antibody
    Background
    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
    Gene ID
    12525
    NCBI Accession
    NP_001074579
    UniProt
    P01731
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