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Leptin antibody

LEP Reactivity: Human WB, IP, EIA, IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN115495
  • Target See all Leptin (LEP) Antibodies
    Leptin (LEP)
    Reactivity
    • 119
    • 73
    • 71
    • 12
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 168
    • 23
    • 6
    • 5
    • 2
    Rabbit
    Clonality
    • 179
    • 24
    Polyclonal
    Conjugate
    • 100
    • 26
    • 17
    • 9
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This Leptin antibody is un-conjugated
    Application
    • 132
    • 85
    • 64
    • 39
    • 39
    • 38
    • 32
    • 30
    • 24
    • 20
    • 16
    • 11
    • 10
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    The antibody was raised in rabbits by immunization with the recombinant Human Leptin.
    Purification
    Immunoaffinity chromatography
    Immunogen
    Recombinant human Leptin (E. coli).
    Top Product
    Discover our top product LEP Primary Antibody
  • Application Notes
    ELISA. Immunohistochemistry. Immunoprecipitation. Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with 0.1 mL of deionized water
    Concentration
    1.0 mg/mL
    Buffer
    0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE
    Preservative
    Azide free
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
    Expiry Date
    6 months
  • Target
    Leptin (LEP)
    Alternative Name
    Leptin (LEP Products)
    Synonyms
    ob antibody, obese antibody, LEPD antibody, OB antibody, OBS antibody, leptin antibody, Lep antibody, LEP antibody, lep antibody
    Background
    Leptin, the product of the ob (obese) gene, is a single-chain 16 kDa proteohormone consisting of 146 amino acid residues. Leptin is produced by differentiated adiocytes, although production have been demonstrated in other tissues, such as fundus of the stomach, the sceletal muscle, the liver, and the placenta. Leptin is considered to play an important role in appetite control, fat metabolism and body weight regulation. It targets the central nervous system, in particular the hypothalamus, suppressing food intake and stimulating energy expenditure. In humans, leptin levels correlate with body mass index (BMI) and percentage body fat, and are elevated even in obese individuals. Leptin has a dual action, it decreases the appetite and increases energy consumption, causing more fat to be burned.Synonyms: LEP, OB, OBS, Obese protein, Obesity factor
    Gene ID
    3952
    NCBI Accession
    NP_000221
    UniProt
    P41159
    Pathways
    JAK-STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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