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Ccl21a antibody

CCL21A Reactivity: Mouse WB, EIA, Func Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN115921
  • Target See all Ccl21a (CCL21A) Antibodies
    Ccl21a (CCL21A) (Chemokine (C-C Motif) Ligand 21A (Serine) (CCL21A))
    Reactivity
    • 2
    • 1
    • 1
    Mouse
    Host
    • 2
    Rabbit
    Clonality
    • 2
    Polyclonal
    Conjugate
    • 1
    • 1
    This Ccl21a antibody is un-conjugated
    Application
    Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)
    Specificity
    This antibody recognises Murine Exodus-2.
    Purification
    Affinity chromatography.
    Immunogen
    Highly pure (>98%) recombinant Mouse Exodus-2.
    Top Product
    Discover our top product CCL21A Primary Antibody
  • Application Notes
    Neutralisation: To yield one-half maximal inhibition [ND50] of the biological activity of mExodus-2 (100.0 ng/mL), a concentration of 9.0-10.0 μg/mL of this antibody is required. ELISA: To detect mExodus-2 by direct ELISA (using 100 l/well antibody solution) a concentrationof at least 0.5 μg/mL of this antibody is required. This antigen affinity purified antibody, inconjunction with compatible secondary reagents, allows the detection of 0.2-0.4 ng/wellof recombinant mExodus-2. Western blot: To detect mExodus-2 by Western Blot analysis this antibody can be used at a concentrationof 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detectionlimit for recombinant mExodus-2 is 1.5-3.0 ng/lane, under either reducing or non-reducingconditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
    Buffer
    PBS, pH 7.2 without preservatives.
    Preservative
    Without preservative
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • Target
    Ccl21a (CCL21A) (Chemokine (C-C Motif) Ligand 21A (Serine) (CCL21A))
    Alternative Name
    6Ckine / CCL21a (CCL21A Products)
    Synonyms
    6CKBAC2 antibody, 6Ckine antibody, ALP antibody, AW987545 antibody, CKb9 antibody, SCYA21a antibody, SLC antibody, Scya21 antibody, Scya21b antibody, Tca4 antibody, plt antibody, chemokine (C-C motif) ligand 21A (serine) antibody, Ccl21a antibody
    Background
    Exodus 2 is one of several CC cytokine genes clustered on the p arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterised by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).Synonyms: Beta chemokine exodus-2, C-C motif chemokine 21a, Scya21a, Small-inducible cytokine A21a, TCA-4, TCA4, Thymus-derived chemotactic agent 4
    Gene ID
    100039131
    NCBI Accession
    NP_035465
    UniProt
    P84443
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