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TNFSF9 antibody (Extracellular Domain)
TNFSF9
Reactivity: Human
WB, ELISA, FACS, ICC
Host: Mouse
Monoclonal
41B436
unconjugated
Product Details anti-TNFSF9 Antibody
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Target
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TNFSF9
(Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
Binding Specificity
All epitopes for TNFSF9 antibodies
Extracellular Domain
Reactivity
All reactivities for TNFSF9 antibodies
Human
Host
All hosts for TNFSF9 antibodies
Mouse
Clonality
All clonalities for TNFSF9 antibodies
Monoclonal
Conjugate
All conjugates for TNFSF9 antibodies
This TNFSF9 antibody is un-conjugated
Application
All applications for TNFSF9 antibodies
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
Specificity
Recognizes extracellular domain of human CD137L.
Cross-Reactivity
Human
No Cross-Reactivity
Mouse (Murine)
Cross-Reactivity (Details)
Does not cross-react with mouse CD137L.
Sterility
0.2 μm filtered
Immunogen
Recombinant human CD137L extracellular domain.
Clone
41B436
Isotype
IgG1
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Discover our top product TNFSF9 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
Lot specific
Buffer
0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Preservative
Without preservative
Storage
4 °C,-20 °C
Storage Comment
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date
12 months
References for anti-TNFSF9 antibody (ABIN1169256)
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Gullo, Koh, Pang, Ho, Tan, Schwarz : "Inhibition of proliferation and induction of apoptosis in multiple myeloma cell lines by CD137 ligand signaling. " in: PLoS ONE , Vol. 5 , Issue 5 , pp. e10845 , (2010 ) (PubMed ).
Target Details for TNFSF9
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Target
TNFSF9
(Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
Alternative Name
CD137L (TNFSF9 Products )
Synonyms
TNFSF9 antibody, 4-1BB-L antibody, 4-1BBL antibody, AI848817 antibody, Cd137l antibody, Ly63l antibody, CD137L antibody, TNF superfamily member 9 antibody, tumor necrosis factor (ligand) superfamily, member 9 antibody, Tnfsf9 antibody, LOC476729 antibody, TNFSF9 antibody
Background
The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response.
UniProt
P41273
Pathways
Activated T Cell Proliferation , Cancer Immune Checkpoints
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