C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (Extracellular Domain) antibody
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| Synonyms |
MER, RP38, c-mer, MGC133349, Eyk, Mer, Nyk, rdy, C-EYK, MERTK, DKFZp469D2215, si:ch1073-268l12.2 |
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Binding Site
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| Clonality |
Monoclonal (A311F9G3) |
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Host
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Reactivity
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Conjugate
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Application
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| Catalog no. |
ABIN1169695 |
| Quantity |
50 µL (Variants) |
| Price |
297.00 $ Plus shipping costs $45.00
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| Shipping to |
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| Availability |
Will be delivered in 5 to 6 Business Days |
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Alternative name
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MERTK (Mer Receptor Tyrosine Kinase)
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Immunogen
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Mer extracellular domain
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Format
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Liquid
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Isotype
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IgG1 kappa
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Clone
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A311F9G3
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Description
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This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
Myeloma: FOX NY mouse myeloma
Synonyms: c MER antibody,c mer proto oncogene tyrosine kinase antibody,cMER antibody,cmer protooncogene tyrosine kinase antibody
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Specificity
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Human Mer
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Application Notes
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Optimal antibody dilution should be determined by titration, however as a guideline use at 1:1000 for western blot
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Purification
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Protein G
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Buffer
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PBS, 0.1% sodium azide
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Preservative
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0.1% Sodium azide
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Restrictions
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For Research Use only
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Product
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Graham, Dawson, Mullaney et al.: "Cloning and mRNA expression analysis of a novel human protooncogene, c-mer." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 5, Issue 6, pp. 647-57, 1994 (PubMed).
Graham, Salzberg, Kurtzberg et al.: "Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 12, Issue 9, pp. 2662-9, 2006 (PubMed).
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Alternatives for antigen "C-Mer Proto-Oncogene Tyrosine Kinase (MERTK)", type "Antibodies"
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Hosts
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Rabbit (35), Mouse (9), Goat (3), Rat (1)
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Reactivities
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Human (44), Mouse (Murine) (24), Rat (Rattus) (21), Monkey (3)
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Applications
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Western Blotting (WB) (29), ELISA (17), Immunofluorescence (IF) (16), Immunoprecipitation (IP) (5), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Flow Cytometry (FACS) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunohistochemistry (IHC) (2), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Epitopes
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Extracellular Domain (3), N-Term (2), AA 200-250 (1), AA 50-100 (1), AA 746-757 (1), C-Term (1), Phosphospecific (1)
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