CD16 antibody
(1 reference)-
- Target See all CD16 Antibodies
- CD16
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD16 antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Brand
- BD Pharmingen™
- Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
- Immunogen
- Human polymorphonuclear leukocytes
- Clone
- 3G8
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD16 Primary Antibody
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anti-CD16 (CD16) antibody
CD16 Reactivity: Human, Non-Human Primate FACS, IP, IHC (fro) Host: Mouse Monoclonal 3G8 unconjugated
anti-CD16 (CD16) antibody (FITC)CD16 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal LNK16 FITC
anti-CD16 (CD16) antibodyCD16 Reactivity: Human FACS, IP, WB Host: Mouse Monoclonal MEM-154 unconjugated
anti-CD16 (CD16) antibodyCD16 Reactivity: Human, Pig, Non-Human Primate FACS Host: Mouse Monoclonal MEM-168 unconjugated
anti-CD16 (CD16) antibodyCD16 Reactivity: Human FACS, IP, WB, Func Host: Mouse Monoclonal MEM-154 unconjugated
anti-CD16 (CD16) antibody (Biotin)CD16 Reactivity: Human FACS, IP, WB Host: Mouse Monoclonal MEM-154 Biotin
anti-CD16 (CD16) (AA 17-208) antibodyCD16 Reactivity: Human FACS, WB, IHC, ELISA, ICC, Neut Host: Mouse Monoclonal 2G10A9 unconjugated
anti-CD16 (CD16) antibodyCD16 Reactivity: Human, Non-Human Primate FACS, IP, Func, IHC (fro) Host: Mouse Monoclonal 3G8 unconjugated
anti-CD16 (CD16) antibody (PE-DyLight 594)CD16 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal 3G8 PE-DyLight 594
anti-CD16 (CD16) antibodyCD16 Reactivity: Human FACS Host: Mouse Monoclonal GRM1 unconjugated
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
- Preservative
- Azide free
- Storage
- 4 °C
- Storage Comment
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "Signal transduction by Fc gamma RIII (CD16) is mediated through the gamma chain." in: The Journal of experimental medicine, Vol. 175, Issue 5, pp. 1381-90, (1992) (PubMed).
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: "Signal transduction by Fc gamma RIII (CD16) is mediated through the gamma chain." in: The Journal of experimental medicine, Vol. 175, Issue 5, pp. 1381-90, (1992) (PubMed).
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- Target
- CD16
- Alternative Name
- CD16 (CD16 Products)
- Synonyms
- Fcgr3 antibody, Fcgr3a antibody, CD16 antibody, FCGR3 antibody, FCGR3@ antibody, CD16b antibody, FCG3 antibody, FCR-10 antibody, FCRIII antibody, FCRIIIb antibody, FcRIII antibody, Fc fragment of IgG, low affinity IIa, receptor antibody, Fc fragment of IgG, low affinity IIIa, receptor (CD16a) antibody, Fc fragment of IgG receptor IIIb antibody, Fc fragment of IgG receptor IIIa antibody, Fc receptor, IgG, low affinity III antibody, Fc-gamma RIII antibody, Fcgr2a antibody, FCGR3A antibody, FCGR3B antibody, Fcgr3 antibody, FCGR3 antibody
- Background
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The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (FcgammaRIII), a human NK-cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes.
Synonyms: FcRIII, Fc-gamma RIII, FCG3, FCGR3, FCGRIII, FcgammaRIII, IGFR3 - Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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